Prediction of Prediabetes and its Prevention by Functional Food Compounds

S. J. Chen, T. Matsui

研究成果: Chapter in Book/Report/Conference proceedingChapter

抄録

Prediabetes, typically defined as impaired glucose tolerance, is a high-risk state of developing diabetes. Although there have considerable scientific progresses in related areas, the extended research concerning antidiabetic action of natural compounds at prediabetic stage has been limited due to the lack of specific biomarkers that enable to identify prediabetes state and elucidate the complicated mechanism of antidiabetic action of natural compounds. The increased formation and accumulation of advanced glycation end products (AGEs) have been confirmed as a vital risk of developing hyperglycemia, type 2 diabetes, and diabetic complications. Many researches revealed that AGEs have showed great potential to be served as biomarkers to predict prediabetic condition. The present chapter is aimed to offer an overview of prediabetes and the current research outcomes involved with functionally natural compounds in decreasing the risk of developing diabetes at prediabetic stage.

本文言語英語
ホスト出版物のタイトルDiscovery and Development of Antidiabetic Agents from Natural Products
ホスト出版物のサブタイトルNatural Product Drug Discovery
出版社Elsevier Inc.
ページ209-228
ページ数20
ISBN(電子版)9780128096925
ISBN(印刷版)9780128094501
DOI
出版ステータス出版済み - 1 1 2017

All Science Journal Classification (ASJC) codes

  • 化学 (全般)

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