Prevalence and Risk Factors for Polypoidal Choroidal Vasculopathy in a General Japanese Population: The Hisayama Study

Kohta Fujiwara, Miho Yasuda, Jun Hata, Yuji Oshima, Sawako Hashimoto, Takeshi Yoshitomi, Yutaka Kiyohara, Tatsuro Ishibashi, Toshiharu Ninomiya, Koh Hei Sonoda

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)


Purpose: To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. Methods: This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old were enrolled in this study. The characteristics of PCV were determined by fundus examination or based on indocyanine green and fluorescein angiographic findings. We evaluated the contributions of the risk factors for PCV. Results: Among the 207 participants with age-related macular degeneration (AMD), 174 (6.5%) had early AMD, and 33 (1.2%) had late AMD, including 10 participants with PCV (0.4%). Male and smoking habit were significant risk factors for the development of PCV. Conclusions: The prevalence of PCV is higher among Japanese subjects than Caucasians in Western countries. Male gender and smoking habit were significant risk factors for PCV in a general Japanese population.

ジャーナルSeminars in Ophthalmology
出版物ステータス出版済み - 8 18 2018


All Science Journal Classification (ASJC) codes

  • Ophthalmology