抄録
The aim of the present study was to examine the prevalence and causes of adult epilepsy in a general Japanese population. We examined a total of 3333 Japanese residents in the town of Hisayama aged ≥40 years in 2012-2013. The examination was performed mainly at the municipal center for health promotion, but some subjects were examined in their homes, hospitals, or nursing homes. Twenty-three subjects had a diagnosis of epilepsy. The prevalence (95% confidence interval [CI]) of epilepsy per 1000 was 6.9 (4.1-9.7) in total, 4.9 (1.3-8.5) in men, and 8.4 (4.3-12.5) in women (P = 0.23 between sexes). The prevalence of epilepsy was significantly higher in the elderly (aged ≥65 years; 10.3 per 1000 [95% CI 5.4-15.1]) than in the middle-aged (aged 40-64 years; 3.6 per 1000 [95% CI 0.7-6.4]; P = 0.02). The major cause of epilepsy was cerebrovascular diseases (n = 11; 48% of the epilepsy patients). More than half of the epilepsy patients experienced the first episode of seizure in older age (≥65 years; n = 13; 57%). The findings of this study suggest the clinical importance of the prevention of cerebrovascular diseases to reduce the burden of epilepsy in the future.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 182-186 |
| ページ数 | 5 |
| ジャーナル | Epilepsia Open |
| 巻 | 4 |
| 発行部数 | 1 |
| DOI | |
| 出版物ステータス | 出版済み - 3 1 2019 |
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All Science Journal Classification (ASJC) codes
- Clinical Neurology
- Neurology
これを引用
Prevalence of adult epilepsy in a general Japanese population : The Hisayama study. / Tanaka, Akihiro; Hata, Jun; Akamatsu, Naoki; Mukai, Naoko; Hirakawa, Yoichiro; Yoshida, Daigo; Kishimoto, Hiro; Ohara, Tomoyuki; Mizuno, Toshiki; Tsuji, Sadatoshi; Kitazono, Takanari; Ninomiya, Toshiharu.
：: Epilepsia Open, 巻 4, 番号 1, 01.03.2019, p. 182-186.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Prevalence of adult epilepsy in a general Japanese population
T2 - The Hisayama study
AU - Tanaka, Akihiro
AU - Hata, Jun
AU - Akamatsu, Naoki
AU - Mukai, Naoko
AU - Hirakawa, Yoichiro
AU - Yoshida, Daigo
AU - Kishimoto, Hiro
AU - Ohara, Tomoyuki
AU - Mizuno, Toshiki
AU - Tsuji, Sadatoshi
AU - Kitazono, Takanari
AU - Ninomiya, Toshiharu
PY - 2019/3/1
Y1 - 2019/3/1
N2 - The aim of the present study was to examine the prevalence and causes of adult epilepsy in a general Japanese population. We examined a total of 3333 Japanese residents in the town of Hisayama aged ≥40 years in 2012-2013. The examination was performed mainly at the municipal center for health promotion, but some subjects were examined in their homes, hospitals, or nursing homes. Twenty-three subjects had a diagnosis of epilepsy. The prevalence (95% confidence interval [CI]) of epilepsy per 1000 was 6.9 (4.1-9.7) in total, 4.9 (1.3-8.5) in men, and 8.4 (4.3-12.5) in women (P = 0.23 between sexes). The prevalence of epilepsy was significantly higher in the elderly (aged ≥65 years; 10.3 per 1000 [95% CI 5.4-15.1]) than in the middle-aged (aged 40-64 years; 3.6 per 1000 [95% CI 0.7-6.4]; P = 0.02). The major cause of epilepsy was cerebrovascular diseases (n = 11; 48% of the epilepsy patients). More than half of the epilepsy patients experienced the first episode of seizure in older age (≥65 years; n = 13; 57%). The findings of this study suggest the clinical importance of the prevention of cerebrovascular diseases to reduce the burden of epilepsy in the future.
AB - The aim of the present study was to examine the prevalence and causes of adult epilepsy in a general Japanese population. We examined a total of 3333 Japanese residents in the town of Hisayama aged ≥40 years in 2012-2013. The examination was performed mainly at the municipal center for health promotion, but some subjects were examined in their homes, hospitals, or nursing homes. Twenty-three subjects had a diagnosis of epilepsy. The prevalence (95% confidence interval [CI]) of epilepsy per 1000 was 6.9 (4.1-9.7) in total, 4.9 (1.3-8.5) in men, and 8.4 (4.3-12.5) in women (P = 0.23 between sexes). The prevalence of epilepsy was significantly higher in the elderly (aged ≥65 years; 10.3 per 1000 [95% CI 5.4-15.1]) than in the middle-aged (aged 40-64 years; 3.6 per 1000 [95% CI 0.7-6.4]; P = 0.02). The major cause of epilepsy was cerebrovascular diseases (n = 11; 48% of the epilepsy patients). More than half of the epilepsy patients experienced the first episode of seizure in older age (≥65 years; n = 13; 57%). The findings of this study suggest the clinical importance of the prevention of cerebrovascular diseases to reduce the burden of epilepsy in the future.
UR - http://www.scopus.com/inward/record.url?scp=85062431540&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85062431540&partnerID=8YFLogxK
U2 - 10.1002/epi4.12295
DO - 10.1002/epi4.12295
M3 - Article
VL - 4
SP - 182
EP - 186
JO - Epilepsia Open
JF - Epilepsia Open
SN - 2470-9239
IS - 1
ER -