Prevalence of adult epilepsy in a general Japanese population: The Hisayama study

Akihiro Tanaka, Jun Hata, Naoki Akamatsu, Naoko Mukai, Yoichiro Hirakawa, Daigo Yoshida, Hiro Kishimoto, Tomoyuki Ohara, Toshiki Mizuno, Sadatoshi Tsuji, Takanari Kitazono, Toshiharu Ninomiya

研究成果: ジャーナルへの寄稿記事

抄録

The aim of the present study was to examine the prevalence and causes of adult epilepsy in a general Japanese population. We examined a total of 3333 Japanese residents in the town of Hisayama aged ≥40 years in 2012-2013. The examination was performed mainly at the municipal center for health promotion, but some subjects were examined in their homes, hospitals, or nursing homes. Twenty-three subjects had a diagnosis of epilepsy. The prevalence (95% confidence interval [CI]) of epilepsy per 1000 was 6.9 (4.1-9.7) in total, 4.9 (1.3-8.5) in men, and 8.4 (4.3-12.5) in women (P = 0.23 between sexes). The prevalence of epilepsy was significantly higher in the elderly (aged ≥65 years; 10.3 per 1000 [95% CI 5.4-15.1]) than in the middle-aged (aged 40-64 years; 3.6 per 1000 [95% CI 0.7-6.4]; P = 0.02). The major cause of epilepsy was cerebrovascular diseases (n = 11; 48% of the epilepsy patients). More than half of the epilepsy patients experienced the first episode of seizure in older age (≥65 years; n = 13; 57%). The findings of this study suggest the clinical importance of the prevention of cerebrovascular diseases to reduce the burden of epilepsy in the future.

元の言語英語
ページ(範囲)182-186
ページ数5
ジャーナルEpilepsia Open
4
発行部数1
DOI
出版物ステータス出版済み - 3 2019

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Epilepsy
Population
Cerebrovascular Disorders
Confidence Intervals
Tonic-Clonic Epilepsy
Nursing Homes
Health Promotion
Seizures

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

これを引用

Prevalence of adult epilepsy in a general Japanese population : The Hisayama study. / Tanaka, Akihiro; Hata, Jun; Akamatsu, Naoki; Mukai, Naoko; Hirakawa, Yoichiro; Yoshida, Daigo; Kishimoto, Hiro; Ohara, Tomoyuki; Mizuno, Toshiki; Tsuji, Sadatoshi; Kitazono, Takanari; Ninomiya, Toshiharu.

:: Epilepsia Open, 巻 4, 番号 1, 03.2019, p. 182-186.

研究成果: ジャーナルへの寄稿記事

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abstract = "The aim of the present study was to examine the prevalence and causes of adult epilepsy in a general Japanese population. We examined a total of 3333 Japanese residents in the town of Hisayama aged ≥40 years in 2012-2013. The examination was performed mainly at the municipal center for health promotion, but some subjects were examined in their homes, hospitals, or nursing homes. Twenty-three subjects had a diagnosis of epilepsy. The prevalence (95{\%} confidence interval [CI]) of epilepsy per 1000 was 6.9 (4.1-9.7) in total, 4.9 (1.3-8.5) in men, and 8.4 (4.3-12.5) in women (P = 0.23 between sexes). The prevalence of epilepsy was significantly higher in the elderly (aged ≥65 years; 10.3 per 1000 [95{\%} CI 5.4-15.1]) than in the middle-aged (aged 40-64 years; 3.6 per 1000 [95{\%} CI 0.7-6.4]; P = 0.02). The major cause of epilepsy was cerebrovascular diseases (n = 11; 48{\%} of the epilepsy patients). More than half of the epilepsy patients experienced the first episode of seizure in older age (≥65 years; n = 13; 57{\%}). The findings of this study suggest the clinical importance of the prevention of cerebrovascular diseases to reduce the burden of epilepsy in the future.",
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