Prevention of the incidence of diabetes by dietary sorbose in nonobese diabetic mice

Mitsuhiro Furuse, C. Kimura, H. Takahashi, J. I. Okumura

研究成果: ジャーナルへの寄稿学術誌査読

6 被引用数 (Scopus)

抄録

The effect of dietary sorbose on the prevention of the incidence of diabetes in the nonobese diabetic mouse was investigated in animals from 5 to 11 wk of age. When sucrose (200 g/kg diet) in the control diet was replaced by sorbose, body weight was significantly reduced. The blood glucose level also was lowered in mice fed sorbose, but the serum insulin level was unchanged. Glucose was not detected in the urine of mice fed the sorbose diet during the experiment, but some mice in the control group excreted glucose in urine. Relative weights of the heart, liver and left kidney were significantly higher in mice fed the sorbose diet vs. those fed the control diet. The results suggest that dietary sorbose would benefit patients with diabetes by lowering blood glucose and inhibiting urinary glucose excretion.

本文言語英語
ページ(範囲)1135-1138
ページ数4
ジャーナルJournal of Nutrition
121
7
DOI
出版ステータス出版済み - 1月 1 1991
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 医学(その他)
  • 栄養および糖尿病

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