Primary mediastinal non-seminomatous germ cell tumor associated with hemophagocytic syndrome.

Eriko Sada, Motoaki Shiratsuchi, Junnichi Kiyasu, Kensaku Idutsu, Rie Ohtsuka, Eriko Nagasawa, Kennosuke Karube, Ryoichi Takayanagi, Yasunobu Abe

研究成果: ジャーナルへの寄稿評論記事

8 引用 (Scopus)

抄録

A 20-year-old man with a primary non-seminomatous mediastinal germ cell tumor (yolk sac tumor and immature teratoma) developed hemophagocytic syndrome (HPS) three months after surgical resection. Around the same time, the patient was found to have bone metastases of the germ cell tumor. No other hereditary or acquired diseases related to HPS were found. The thrombocytopenia was refractory to corticosteroid therapy but improved after chemotherapy performed for germ cell tumor progression. Only three cases of germ cell tumor associated with reactive hemophagocytosis have been previously reported. Successful treatment of the present case by chemotherapy for HPS suggests a close relationship between this rare complication and germ cell tumor.

元の言語英語
ページ(範囲)117-120
ページ数4
ジャーナルJournal of clinical and experimental hematopathology : JCEH
49
発行部数2
DOI
出版物ステータス出版済み - 11 2009

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Hemophagocytic Lymphohistiocytosis
Germ Cell and Embryonal Neoplasms
Endodermal Sinus Tumor
Drug Therapy
Teratoma
Thrombocytopenia
Adrenal Cortex Hormones
Neoplasm Metastasis
Bone and Bones
Nonseminomatous germ cell tumor
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Primary mediastinal non-seminomatous germ cell tumor associated with hemophagocytic syndrome. / Sada, Eriko; Shiratsuchi, Motoaki; Kiyasu, Junnichi; Idutsu, Kensaku; Ohtsuka, Rie; Nagasawa, Eriko; Karube, Kennosuke; Takayanagi, Ryoichi; Abe, Yasunobu.

:: Journal of clinical and experimental hematopathology : JCEH, 巻 49, 番号 2, 11.2009, p. 117-120.

研究成果: ジャーナルへの寄稿評論記事

Sada, Eriko ; Shiratsuchi, Motoaki ; Kiyasu, Junnichi ; Idutsu, Kensaku ; Ohtsuka, Rie ; Nagasawa, Eriko ; Karube, Kennosuke ; Takayanagi, Ryoichi ; Abe, Yasunobu. / Primary mediastinal non-seminomatous germ cell tumor associated with hemophagocytic syndrome. :: Journal of clinical and experimental hematopathology : JCEH. 2009 ; 巻 49, 番号 2. pp. 117-120.
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abstract = "A 20-year-old man with a primary non-seminomatous mediastinal germ cell tumor (yolk sac tumor and immature teratoma) developed hemophagocytic syndrome (HPS) three months after surgical resection. Around the same time, the patient was found to have bone metastases of the germ cell tumor. No other hereditary or acquired diseases related to HPS were found. The thrombocytopenia was refractory to corticosteroid therapy but improved after chemotherapy performed for germ cell tumor progression. Only three cases of germ cell tumor associated with reactive hemophagocytosis have been previously reported. Successful treatment of the present case by chemotherapy for HPS suggests a close relationship between this rare complication and germ cell tumor.",
author = "Eriko Sada and Motoaki Shiratsuchi and Junnichi Kiyasu and Kensaku Idutsu and Rie Ohtsuka and Eriko Nagasawa and Kennosuke Karube and Ryoichi Takayanagi and Yasunobu Abe",
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AU - Sada, Eriko

AU - Shiratsuchi, Motoaki

AU - Kiyasu, Junnichi

AU - Idutsu, Kensaku

AU - Ohtsuka, Rie

AU - Nagasawa, Eriko

AU - Karube, Kennosuke

AU - Takayanagi, Ryoichi

AU - Abe, Yasunobu

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