Primary mediastinal non-seminomatous germ cell tumor associated with hemophagocytic syndrome.

Eriko Sada, Motoaki Shiratsuchi, Junnichi Kiyasu, Kensaku Idutsu, Rie Ohtsuka, Eriko Nagasawa, Kennosuke Karube, Ryoichi Takayanagi, Yasunobu Abe

研究成果: Contribution to journalReview article査読

8 被引用数 (Scopus)

抄録

A 20-year-old man with a primary non-seminomatous mediastinal germ cell tumor (yolk sac tumor and immature teratoma) developed hemophagocytic syndrome (HPS) three months after surgical resection. Around the same time, the patient was found to have bone metastases of the germ cell tumor. No other hereditary or acquired diseases related to HPS were found. The thrombocytopenia was refractory to corticosteroid therapy but improved after chemotherapy performed for germ cell tumor progression. Only three cases of germ cell tumor associated with reactive hemophagocytosis have been previously reported. Successful treatment of the present case by chemotherapy for HPS suggests a close relationship between this rare complication and germ cell tumor.

本文言語英語
ページ(範囲)117-120
ページ数4
ジャーナルJournal of clinical and experimental hematopathology : JCEH
49
2
DOI
出版ステータス出版済み - 11 2009

All Science Journal Classification (ASJC) codes

  • 医学(全般)

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