Production of daunorubicin by immobilized growing Streptomyces peucetius cells

Yoshiki Takashima, Hiroki Nakajima, Kenji Sonomoto, Atsuo Tanaka

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

抄録

Streptomyces peucetius cells were immobilized by entrapment in calcium alginate and a photosensitive synthetic polymer, and used for the production of daunorubicin (daunomycin), which is known to be an antitumour reagent. The use of cultivation media removed insoluble components in a natural medium prevented rapid decrease in daunorubicin titer after maximum production. These entrapped cells could be used at least five times for repeated daunorubicin production; the total cultivation period was 45 days.

元の言語英語
ページ(範囲)106-109
ページ数4
ジャーナルApplied Microbiology and Biotechnology
27
発行部数2
DOI
出版物ステータス出版済み - 11 1 1987

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Daunorubicin
Streptomyces
Immobilized Cells
Polymers

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology

これを引用

Production of daunorubicin by immobilized growing Streptomyces peucetius cells. / Takashima, Yoshiki; Nakajima, Hiroki; Sonomoto, Kenji; Tanaka, Atsuo.

:: Applied Microbiology and Biotechnology, 巻 27, 番号 2, 01.11.1987, p. 106-109.

研究成果: ジャーナルへの寄稿記事

Takashima, Yoshiki ; Nakajima, Hiroki ; Sonomoto, Kenji ; Tanaka, Atsuo. / Production of daunorubicin by immobilized growing Streptomyces peucetius cells. :: Applied Microbiology and Biotechnology. 1987 ; 巻 27, 番号 2. pp. 106-109.
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