Production of daunorubicin by immobilized growing Streptomyces peucetius cells

Yoshiki Takashima, Hiroki Nakajima, Kenji Sonomoto, Atsuo Tanaka

研究成果: Contribution to journalArticle査読

13 被引用数 (Scopus)

抄録

Streptomyces peucetius cells were immobilized by entrapment in calcium alginate and a photosensitive synthetic polymer, and used for the production of daunorubicin (daunomycin), which is known to be an antitumour reagent. The use of cultivation media removed insoluble components in a natural medium prevented rapid decrease in daunorubicin titer after maximum production. These entrapped cells could be used at least five times for repeated daunorubicin production; the total cultivation period was 45 days.

本文言語英語
ページ(範囲)106-109
ページ数4
ジャーナルApplied Microbiology and Biotechnology
27
2
DOI
出版ステータス出版済み - 11 1 1987

All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • 応用微生物学とバイオテクノロジー

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