Prognostic factors in patients with submucosal carcinoma of the oesophagus

M. Watanabe, H. Kuwano, K. Araki, H. Kawaguchi, H. Saeki, K. Kitamura, S. Ohno, K. Sugimachi

研究成果: Contribution to journalArticle査読

36 被引用数 (Scopus)

抄録

To clarify the prognostic factors in patients with submucosal carcinoma of the oesophagus, we examined the results of surgical treatment for 78 cases over the last decade. The clinicopathological factors including age, sex, location of the tumour, length of the tumour, histological difterentiation, subclassification of depth, lymphatic or blood vessel invasion, intramural metastasis and lymph node metastasis were all analysed. Then the correlation between these factors and prognosis was investigated. As a result, significant differences were observed in the survival rates between the groups regarding lymphatic vessel invasion (P = 0.0003), intramural metastasis (P = 0.0051) and lymph node metastasis (P= 0.0026). According to a multivariate analysis, intramural metastasis (P = 0.0038, relative risk 9.17), vessel invasion (P= 0.0033, relative risk 6.25) and lymph node metastasis (P= 0.0187, relative risk 3.62) were found to be independent prognostic factors. The prognosis of the patients with at least one of these factors was significantly poorer than that without. The five-year survival rate of the patients without these factors was as good as that with mucosal carcinoma of the oesophagus. Based on our findings, vessel invasion, intramural metastasis and lymph node metastasis are thus considered to be significant prognostic factors in patients with submucosal carcinoma of the oesophagus. (C) 2000 Cancer Research Campaign.

本文言語英語
ページ(範囲)609-613
ページ数5
ジャーナルBritish journal of cancer
83
5
DOI
出版ステータス出版済み - 2000
外部発表はい

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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