抄録
Background: To evaluate the prognostic outcome and surgical complications in patients with early-stage cervical cancer who underwent sentinel node navigation surgery (SNNS) for hysterectomy or trachelectomy. Methods: A total of 139 patients who underwent SNNS using 99mTc phytate between 2009 and 2015 were evaluated. No further lymph node dissection was performed when intraoperative analysis of the sentinel lymph nodes (SLNs) was negative for metastasis. We compared the surgical complications between the SNNS group and 67 matched patients who underwent pelvic lymph node dissection (PLND) after SLN mapping between 2003 and 2008. We also examined the clinical outcomes in the SNNS group. Results: The mean number of detected SLNs was 2.5 per patient. Fourteen of the 139 patients in the SNNS group underwent PLND based on the intraoperative SLN results. The amount of blood loss, the operative time, and the number of perioperative complications were significantly less in the SNNS group than in the matched PLND group. There was no recurrence during a follow-up period ranging from 2 to 88 months (median 40 months) in the SNNS group. Conclusions: Using SNNS for early-stage cervical cancer is safe and effective and does not increase the recurrence rate. A future multicenter trial is warranted.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 1167-1172 |
| ページ数 | 6 |
| ジャーナル | International Journal of Clinical Oncology |
| 巻 | 23 |
| 発行部数 | 6 |
| DOI | |
| 出版物ステータス | 出版済み - 12 1 2018 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Surgery
- Hematology
- Oncology
これを引用
Prognostic outcome and complications of sentinel lymph node navigation surgery for early-stage cervical cancer. / Yahata, Hideaki; Kobayashi, Hiroaki; Sonoda, Kenzo; Kodama, Keisuke; yagi, hiroshi; Yasunaga, Masafumi; Ogami, Tatsuhiro; Onoyama, Ichiro; Eisuke, Kaneki; Kaoru, Okugawa; Baba, Shingo; Isoda, Takuro; Ohishi, Yoshihiro; Oda, Yoshinao; Kato, Kiyoko.
：: International Journal of Clinical Oncology, 巻 23, 番号 6, 01.12.2018, p. 1167-1172.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Prognostic outcome and complications of sentinel lymph node navigation surgery for early-stage cervical cancer
AU - Yahata, Hideaki
AU - Kobayashi, Hiroaki
AU - Sonoda, Kenzo
AU - Kodama, Keisuke
AU - yagi, hiroshi
AU - Yasunaga, Masafumi
AU - Ogami, Tatsuhiro
AU - Onoyama, Ichiro
AU - Eisuke, Kaneki
AU - Kaoru, Okugawa
AU - Baba, Shingo
AU - Isoda, Takuro
AU - Ohishi, Yoshihiro
AU - Oda, Yoshinao
AU - Kato, Kiyoko
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Background: To evaluate the prognostic outcome and surgical complications in patients with early-stage cervical cancer who underwent sentinel node navigation surgery (SNNS) for hysterectomy or trachelectomy. Methods: A total of 139 patients who underwent SNNS using 99mTc phytate between 2009 and 2015 were evaluated. No further lymph node dissection was performed when intraoperative analysis of the sentinel lymph nodes (SLNs) was negative for metastasis. We compared the surgical complications between the SNNS group and 67 matched patients who underwent pelvic lymph node dissection (PLND) after SLN mapping between 2003 and 2008. We also examined the clinical outcomes in the SNNS group. Results: The mean number of detected SLNs was 2.5 per patient. Fourteen of the 139 patients in the SNNS group underwent PLND based on the intraoperative SLN results. The amount of blood loss, the operative time, and the number of perioperative complications were significantly less in the SNNS group than in the matched PLND group. There was no recurrence during a follow-up period ranging from 2 to 88 months (median 40 months) in the SNNS group. Conclusions: Using SNNS for early-stage cervical cancer is safe and effective and does not increase the recurrence rate. A future multicenter trial is warranted.
AB - Background: To evaluate the prognostic outcome and surgical complications in patients with early-stage cervical cancer who underwent sentinel node navigation surgery (SNNS) for hysterectomy or trachelectomy. Methods: A total of 139 patients who underwent SNNS using 99mTc phytate between 2009 and 2015 were evaluated. No further lymph node dissection was performed when intraoperative analysis of the sentinel lymph nodes (SLNs) was negative for metastasis. We compared the surgical complications between the SNNS group and 67 matched patients who underwent pelvic lymph node dissection (PLND) after SLN mapping between 2003 and 2008. We also examined the clinical outcomes in the SNNS group. Results: The mean number of detected SLNs was 2.5 per patient. Fourteen of the 139 patients in the SNNS group underwent PLND based on the intraoperative SLN results. The amount of blood loss, the operative time, and the number of perioperative complications were significantly less in the SNNS group than in the matched PLND group. There was no recurrence during a follow-up period ranging from 2 to 88 months (median 40 months) in the SNNS group. Conclusions: Using SNNS for early-stage cervical cancer is safe and effective and does not increase the recurrence rate. A future multicenter trial is warranted.
UR - http://www.scopus.com/inward/record.url?scp=85051282693&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85051282693&partnerID=8YFLogxK
U2 - 10.1007/s10147-018-1327-y
DO - 10.1007/s10147-018-1327-y
M3 - Article
C2 - 30094694
AN - SCOPUS:85051282693
VL - 23
SP - 1167
EP - 1172
JO - International Journal of Clinical Oncology
JF - International Journal of Clinical Oncology
SN - 1341-9625
IS - 6
ER -