Prognostic value of combination assays for CEA and CA 19-9 in gastric cancer

Y. Ikeda, H. Oomori, N. Koyanagi, M. Mori, T. Kamakura, S. Minagawa, H. Tateishi, K. Sugimachi

研究成果: Contribution to journalArticle査読

35 被引用数 (Scopus)

抄録

Preoperative serum CEA and CA 19-9 levels in 158 patients with gastric cancer were analyzed with respect to prognostic factors, using univariate and multivariate analysis. The incidence of high preoperative levels of both CEA and CA 19-9 was 10.1% (16/158). 13.9% (22/158) showed high CEA levels and normal CA 19-9 levels, whereas the reverse was true in 16.5% (26/158). Neither marker showed a high level in 59.5% (94/158). The multivariate analysis showed that in addition to tumor stage, the depth of invasion, liver metastasis and peritoneal dissemination, combination assays of preoperative serum CEA and CA 19-9 levels were an independent prognostic factor. Combination assays of preoperative serum CEA and CA 19-9 will allow us to conduct a more careful postoperative follow-up of high-risk patients, and also help determine the optimum adjuvant chemotherapy.

本文言語英語
ページ(範囲)483-486
ページ数4
ジャーナルOncology
52
6
DOI
出版ステータス出版済み - 1995
外部発表はい

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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