Promotion of glycerol utilization using ethanol and 1-propanol in Schizosaccharomyces pombe

Tomohiko Matsuzawa, Futoshi Hara, Hideki Tohda, Hiroshi Uemura, Kaoru Takegawa

研究成果: ジャーナルへの寄稿学術誌査読

4 被引用数 (Scopus)

抄録

The fission yeast Schizosaccharomyces pombe does not grow in media containing glycerol as a sole carbon source but uses glycerol in the presence of ethanol. Ethanol, but not glycerol, triggered upregulation of gld1 + and fbp1 + during glucose starvation even though gld1 + and fbp1 + are essential for growth on glycerol. This upregulation occurred at a very low concentration of ethanol. The transcriptional regulation of gld1 + was tested in the presence of various alcohols, and both ethanol and 1-propanol were found to induce gld1 + and to support growth in glycerol-containing media. We suggest that S. pombe has a novel ethanol and/or 1-propanol recognition mechanism that upregulates glycerol utilization during glucose starvation.

本文言語英語
ページ(範囲)441-449
ページ数9
ジャーナルApplied Microbiology and Biotechnology
95
2
DOI
出版ステータス出版済み - 7月 2012

!!!All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • 応用微生物学とバイオテクノロジー

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