Pseudorabies virus early protein O transactivates the viral gene promoters

S. Watanabe, E. Ono, Y. Shimizu, H. Kida

研究成果: Contribution to journalArticle査読

33 被引用数 (Scopus)

抄録

Pseudorabies virus (PRV) early protein O (EPO) contains the RING finger domain with homology to the immediate-early (IE) protein ICPO of herpes simplex virus type 1 (HSV-I). EPO was detected by indirect immunefluorescence in the nuclei of the cells transfected with EPO expression plasmid as is the case in cells infected with PRV. In transient expression assays, EPO transactivated the PRV IE, thymidine kinase (TK) and glycopretein X (gX) promoters, indicating that EPO, like ICPO of HSV-I, is a transactivating protein.

本文言語英語
ページ(範囲)2881-2885
ページ数5
ジャーナルJournal of General Virology
76
11
DOI
出版ステータス出版済み - 1995
外部発表はい

All Science Journal Classification (ASJC) codes

  • ウイルス学

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