Pursaethosides A-E, triterpene saponins from Entada pursaetha

Azefack Léon Tapondjou, Tomofumi Miyamoto, Jean François Mirjolet, Nicolas Guilbaud, Marie Aleth Lacaille-Dubois

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

抜粋

Five new triterpenoid saponins, pursaethosides A-E (1-5), were isolated from the η-BuOH extract of the seed kernels of Entada pursaetha along with the known phaseoloidin. The structures of 1-5 were elucidated mainly by spectroscopic data interpretation and chemical degradation. Pursaethosides C-E (3-5) possess as a common structural feature entagenic acid as aglycon, which is rare among triterpene saponins. Compounds 2-4 and phaesolidin were found to be not cytotoxic when tested against HCT 116 and HT-29 human colon cancer cells.

元の言語英語
ページ(範囲)1185-1190
ページ数6
ジャーナルJournal of Natural Products
68
発行部数8
DOI
出版物ステータス出版済み - 8 1 2005

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

これを引用

Tapondjou, A. L., Miyamoto, T., Mirjolet, J. F., Guilbaud, N., & Lacaille-Dubois, M. A. (2005). Pursaethosides A-E, triterpene saponins from Entada pursaetha. Journal of Natural Products, 68(8), 1185-1190. https://doi.org/10.1021/np0580311