@article{50e6bc82bea44e24b72bd70f16ea69ce,
title = "Pyrrolo[2,1-a]isoquinolines as multitasking organophotocatalysts in chemical synthesis",
abstract = "We demonstrate the design and synthesis of pyrrolo[2,1-a]isoquinolines (PIqs) bearing electron-withdrawing groups, which are excited under irradiation with visible light to display wider redox windows and higher triplet-state energies. The photophysical and electrochemical characters of PIqs can be tailored by modification of the electron-withdrawing groups and their positions, enabling redox-neutral (hetero)biaryl cross-coupling between aryl halides and (hetero)arenes, nickel-catalyzed amination and oxygenation of aryl halides, and decarboxylative cross-coupling between α-amino acids and aryl halides, as well as a set of molecular transformations driven by triplet-triplet sensitization under irradiation with visible light.",
author = "Yuliang Liu and Haoyu Li and Tan, {Eugene Yew Kun} and Santiko, {Erik Budi} and Youhei Chitose and Manabu Abe and Shunsuke Chiba",
note = "Funding Information: Financial support was provided by Nanyang Technological University (NTU) and the Singapore Ministry of Education (Academic Research Fund Tier 2: MOE2017-T2-1-064) (to S.C.), as well as JSPS KAKENHI grants (JP21H01921 and JP20K21197) and the Uehara Memorial Foundation (to M.A.). We acknowledge Dr. Yongxin Li (Division of Chemistry and Biological Chemistry, NTU) for assistance in X-ray crystallographic analysis. We thank Jean-Philippe Krieger (Syngenta) and Farhan Bou Hamdan (Syngenta) for helpful discussion. Conceptualization and methodology, Y.L. M.A. and S.C.; investigation, Y.L. H.L. E.Y.K.T. E.B.S. and Y.C.; writing – original draft, Y.L. M.A. and S.C.; writing – review & editing, S.C.; funding acquisition, resources, and supervision, M.A. and S.C. The authors declare no competing interests. Funding Information: Financial support was provided by Nanyang Technological University (NTU) and the Singapore Ministry of Education (Academic Research Fund Tier 2: MOE2017-T2-1-064 ) (to S.C.), as well as JSPS KAKENHI grants ( JP21H01921 and JP20K21197 ) and the Uehara Memorial Foundation (to M.A.). We acknowledge Dr. Yongxin Li (Division of Chemistry and Biological Chemistry, NTU) for assistance in X-ray crystallographic analysis. We thank Jean-Philippe Krieger (Syngenta) and Farhan Bou Hamdan (Syngenta) for helpful discussion. Publisher Copyright: {\textcopyright} 2022 The Authors",
year = "2022",
month = oct,
day = "20",
doi = "10.1016/j.checat.2022.08.013",
language = "English",
volume = "2",
pages = "2726--2749",
journal = "Chem Catalysis",
issn = "2667-1107",
publisher = "Cell Press",
number = "10",
}