Quantification of ex vivo tissue activity by short and long time-course analysis of multifunctional OCT signals

I. G. Abd El-Sadek, A. Miyazawa, L. T.W. Shen, S. Fukuda, T. Yamashita, Y. Oka, P. Mukherjee, S. Makita, S. Matsusaka, T. Oshika, H. Kano, Y. Yasuno

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

1 被引用数 (Scopus)

抄録

We present a new OCT-based tissue dynamics/subcellular motion analysis method to visualize tissue dynamics, where we increase the functionality of OCT to be sensitive for tissue dynamics by utilizing rapid-time-sequence analysis of OCT signals. These analysis includes log intensity variance (LIV) and OCT time-correlation analysis (OCT decorrelation speed; OCDS). In addition to LIV and OCDS methods, attenuation coefficient (AC), birefringence, and degree of polarization uniformity (DOPU) analysis were performed. These methods used to visualize and quantify long-term tissue dynamics degradation of different tissue types such as dissected mouse liver and tumor spheroids. These methods were quantitative, so the time-course tissue dynamics degradation has been not only visualized as an image, but also quantitative analysis of the dynamics degradation were performed.

本文言語英語
ホスト出版物のタイトルOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV
編集者Joseph A. Izatt, James G. Fujimoto
出版社SPIE
ISBN(電子版)9781510632196
DOI
出版ステータス出版済み - 2020
外部発表はい
イベントOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV 2020 - San Francisco, 米国
継続期間: 2 3 20202 5 2020

出版物シリーズ

名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE
11228
ISSN(印刷版)1605-7422

会議

会議Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV 2020
Country米国
CitySan Francisco
Period2/3/202/5/20

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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