Quantitative analysis of digestion resistant ACE inhibitory dipeptides by small intestinal mucosa

Eiji Seki, Katsuhiro Osajima, Hiroshi Matsufuji, Toshiro Matsui, Yutaka Osajima

研究成果: ジャーナルへの寄稿学術誌査読

5 被引用数 (Scopus)

抄録

The short chain peptides derived from sardines were incubated for 120 min with an extract of porcine small intestinal mucosa. Digestion-resistant dipeptides found in the digest, Val-Tyr, Val-Trp, Ile-Tyr and Ile-Trp, inhibited angiotensin I converting enzyme (ACE). Amounts of the four dipeptides isolated from the digest using a Sep-pak C-18 cartridge column and three steps of high-performance liquid chromatography, were 85.88, 21.87, 10.69 and 6.51 mg/100 g peptides, respectively, and the contribution of four peptides to total ACE inhibitory activity was 10.5%. It was confirmed that ACE inhibitory dipeptides were present in the digest of the short chain peptides.

本文言語英語
ページ(範囲)967-969
ページ数3
ジャーナルNippon Shokuhin Kagaku Kogaku Kaishi
43
8
DOI
出版ステータス出版済み - 1996

!!!All Science Journal Classification (ASJC) codes

  • 食品科学

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