Quantitative Assessment of Hippocampus Architecture Using the Optical Disector

研究成果: 著書/レポートタイプへの貢献

抄録

The optical disector, one of the most commonly used design-based stereological techniques, enables accurate counting of total number of objects (neurons, synapses) using thick 2D sections through the reference space of interest. The optical disector applied to thick immunostained sections requires attention to several technical issues. Differential shrinkage of tissue presents a major problem for accurate density estimation by the optical disector. The hippocampus, a major limbic structure, and its contribution to learning and memory have consistently attracted the interest of neuroscientists. the hippocampus is composed of complicated 3D networks of neural connections. The authors review the spatial distributions and provide density estimates from optical disector counts of eight classes of GABAergic neurons in the hippocampus defined by the following neurochemical markers: three calcium-binding proteins; four neuropeptides; and neuronal nitric oxide synthase (NOS).

元の言語英語
ホスト出版物のタイトルNeurostereology
ホスト出版物のサブタイトルUnbiased Stereology of Neural Systems
出版者wiley
ページ113-127
ページ数15
ISBN(電子版)9781118444177
ISBN(印刷物)9781118444214
DOI
出版物ステータス出版済み - 11 25 2013

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Hippocampus
GABAergic Neurons
Nitric Oxide Synthase Type I
Calcium-Binding Proteins
Neuropeptides
Synapses
Learning
Neurons

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Neuroscience(all)

これを引用

Jinno, S. (2013). Quantitative Assessment of Hippocampus Architecture Using the Optical Disector. : Neurostereology: Unbiased Stereology of Neural Systems (pp. 113-127). wiley. https://doi.org/10.1002/9781118444177.ch9

Quantitative Assessment of Hippocampus Architecture Using the Optical Disector. / Jinno, Shozo.

Neurostereology: Unbiased Stereology of Neural Systems. wiley, 2013. p. 113-127.

研究成果: 著書/レポートタイプへの貢献

Jinno, S 2013, Quantitative Assessment of Hippocampus Architecture Using the Optical Disector. : Neurostereology: Unbiased Stereology of Neural Systems. wiley, pp. 113-127. https://doi.org/10.1002/9781118444177.ch9
Jinno S. Quantitative Assessment of Hippocampus Architecture Using the Optical Disector. : Neurostereology: Unbiased Stereology of Neural Systems. wiley. 2013. p. 113-127 https://doi.org/10.1002/9781118444177.ch9
Jinno, Shozo. / Quantitative Assessment of Hippocampus Architecture Using the Optical Disector. Neurostereology: Unbiased Stereology of Neural Systems. wiley, 2013. pp. 113-127
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