Question of Covalent Intermediate Formation in the Flavine-Catalyzed Carbonyl to Carbinol Oxidation-Reduction Reaction

Seiji Shinkai, Thomas C. Bruice

研究成果: ジャーナルへの寄稿 › 記事

32 引用 (Scopus)

抄録

The mechanisms by which flavoenzymes catalyze oxidation-reduction reactions are of much concern. We address ourselves herein to the interconversion of aldehydes (ketones) and alcohols coupled to the oxidation-reduction of flavine. In a study of the oxidation of 10-phenylisoalloxazine Brown and Hamilton1 proposed 4a addition of alkoxide followed by base-catalyzed elimination of ketone (eq 1).

元の言語英語
ページ（範囲）7526-7528
ページ数3
ジャーナルJournal of the American Chemical Society
巻95
発行部数22
DOI
出版物ステータス出版済み - 10 1 1973
外部発表Yes

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Redox reactions
Ketones
Oxidation-Reduction
Methanol
Aldehydes
Alcohols
Oxidation

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

これを引用

Question of Covalent Intermediate Formation in the Flavine-Catalyzed Carbonyl to Carbinol Oxidation-Reduction Reaction. / Shinkai, Seiji; Bruice, Thomas C.

：: Journal of the American Chemical Society, 巻 95, 番号 22, 01.10.1973, p. 7526-7528.

研究成果: ジャーナルへの寄稿 › 記事

Shinkai, S & Bruice, TC 1973, 'Question of Covalent Intermediate Formation in the Flavine-Catalyzed Carbonyl to Carbinol Oxidation-Reduction Reaction', Journal of the American Chemical Society, 巻. 95, 番号 22, pp. 7526-7528. https://doi.org/10.1021/ja00803a064
Shinkai S, Bruice TC. Question of Covalent Intermediate Formation in the Flavine-Catalyzed Carbonyl to Carbinol Oxidation-Reduction Reaction. Journal of the American Chemical Society. 1973 10 1;95(22):7526-7528. https://doi.org/10.1021/ja00803a064
Shinkai, Seiji ; Bruice, Thomas C. / Question of Covalent Intermediate Formation in the Flavine-Catalyzed Carbonyl to Carbinol Oxidation-Reduction Reaction. ：: Journal of the American Chemical Society. 1973 ; 巻 95, 番号 22. pp. 7526-7528.
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