Radiological assessment of hepatic vein invasion by hepatocellular carcinoma using combined computed tomography hepatic arteriography and computed tomography arterial portography

Akihiro Nishie, Tsuyoshi Tajima, Yoshiki Asayama, Kousei Ishigami, Masakazu Hirakawa, Yasuhiro Ushijima, Daisuke Kakihara, Daisuke Okamoto, Nobuhiro Fujita, Akinobu Taketomi, Kengo Yoshimitsu, Hiroshi Honda

研究成果: ジャーナルへの寄稿記事

抄録

Purpose: The aim of this study was to elucidate computed tomography hepatic arteriography (CTHA) and CT arterial portography (CTAP) findings characteristic of hepatocellular carcinoma (HCC) with large hepatic venous invasion (HVI) and then to examine whether the presence of minute HVI can be diagnosed based on each finding. Materials and methods: Combined CTHA and CTAP of 106 HCCs were examined. Two radiologists analyzed the radiological findings of five nodules with large HVI (group vv2). The remaining 101 nodules were classified into two groups: group vv1, positive minute HVI; group vv0, negative HVI. They examined whether each finding observed in group vv2 could be detected in groups vv1 and vv0. Results: Analysis of group vv2 identified (a) tumor thrombus, (b) early inflow of the contrast into the hepatic vein proximal to the invaded site, and (c) partially decreased portal venous flow in the peripheral parenchyma subject to the involved hepatic vein. Findings (b) and (c) were observed in 16% of group vv1. A significant difference in frequency of finding (c) was obtained between groups vv1 and vv0. The positive and negative predictive values of finding (c) were 66.7% and 77.9%, respectively. Conclusion: Findings (b) and (c), especially the latter, may partly contribute to the radiological diagnosis of minute HVI.

元の言語英語
ページ(範囲)414-422
ページ数9
ジャーナルJapanese Journal of Radiology
28
発行部数6
DOI
出版物ステータス出版済み - 7 1 2010

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Portography
Hepatic Veins
Hepatocellular Carcinoma
Angiography
Tomography
Liver
Thrombosis

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

これを引用

Radiological assessment of hepatic vein invasion by hepatocellular carcinoma using combined computed tomography hepatic arteriography and computed tomography arterial portography. / Nishie, Akihiro; Tajima, Tsuyoshi; Asayama, Yoshiki; Ishigami, Kousei; Hirakawa, Masakazu; Ushijima, Yasuhiro; Kakihara, Daisuke; Okamoto, Daisuke; Fujita, Nobuhiro; Taketomi, Akinobu; Yoshimitsu, Kengo; Honda, Hiroshi.

:: Japanese Journal of Radiology, 巻 28, 番号 6, 01.07.2010, p. 414-422.

研究成果: ジャーナルへの寄稿記事

Nishie, Akihiro ; Tajima, Tsuyoshi ; Asayama, Yoshiki ; Ishigami, Kousei ; Hirakawa, Masakazu ; Ushijima, Yasuhiro ; Kakihara, Daisuke ; Okamoto, Daisuke ; Fujita, Nobuhiro ; Taketomi, Akinobu ; Yoshimitsu, Kengo ; Honda, Hiroshi. / Radiological assessment of hepatic vein invasion by hepatocellular carcinoma using combined computed tomography hepatic arteriography and computed tomography arterial portography. :: Japanese Journal of Radiology. 2010 ; 巻 28, 番号 6. pp. 414-422.
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abstract = "Purpose: The aim of this study was to elucidate computed tomography hepatic arteriography (CTHA) and CT arterial portography (CTAP) findings characteristic of hepatocellular carcinoma (HCC) with large hepatic venous invasion (HVI) and then to examine whether the presence of minute HVI can be diagnosed based on each finding. Materials and methods: Combined CTHA and CTAP of 106 HCCs were examined. Two radiologists analyzed the radiological findings of five nodules with large HVI (group vv2). The remaining 101 nodules were classified into two groups: group vv1, positive minute HVI; group vv0, negative HVI. They examined whether each finding observed in group vv2 could be detected in groups vv1 and vv0. Results: Analysis of group vv2 identified (a) tumor thrombus, (b) early inflow of the contrast into the hepatic vein proximal to the invaded site, and (c) partially decreased portal venous flow in the peripheral parenchyma subject to the involved hepatic vein. Findings (b) and (c) were observed in 16{\%} of group vv1. A significant difference in frequency of finding (c) was obtained between groups vv1 and vv0. The positive and negative predictive values of finding (c) were 66.7{\%} and 77.9{\%}, respectively. Conclusion: Findings (b) and (c), especially the latter, may partly contribute to the radiological diagnosis of minute HVI.",
author = "Akihiro Nishie and Tsuyoshi Tajima and Yoshiki Asayama and Kousei Ishigami and Masakazu Hirakawa and Yasuhiro Ushijima and Daisuke Kakihara and Daisuke Okamoto and Nobuhiro Fujita and Akinobu Taketomi and Kengo Yoshimitsu and Hiroshi Honda",
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T1 - Radiological assessment of hepatic vein invasion by hepatocellular carcinoma using combined computed tomography hepatic arteriography and computed tomography arterial portography

AU - Nishie, Akihiro

AU - Tajima, Tsuyoshi

AU - Asayama, Yoshiki

AU - Ishigami, Kousei

AU - Hirakawa, Masakazu

AU - Ushijima, Yasuhiro

AU - Kakihara, Daisuke

AU - Okamoto, Daisuke

AU - Fujita, Nobuhiro

AU - Taketomi, Akinobu

AU - Yoshimitsu, Kengo

AU - Honda, Hiroshi

PY - 2010/7/1

Y1 - 2010/7/1

N2 - Purpose: The aim of this study was to elucidate computed tomography hepatic arteriography (CTHA) and CT arterial portography (CTAP) findings characteristic of hepatocellular carcinoma (HCC) with large hepatic venous invasion (HVI) and then to examine whether the presence of minute HVI can be diagnosed based on each finding. Materials and methods: Combined CTHA and CTAP of 106 HCCs were examined. Two radiologists analyzed the radiological findings of five nodules with large HVI (group vv2). The remaining 101 nodules were classified into two groups: group vv1, positive minute HVI; group vv0, negative HVI. They examined whether each finding observed in group vv2 could be detected in groups vv1 and vv0. Results: Analysis of group vv2 identified (a) tumor thrombus, (b) early inflow of the contrast into the hepatic vein proximal to the invaded site, and (c) partially decreased portal venous flow in the peripheral parenchyma subject to the involved hepatic vein. Findings (b) and (c) were observed in 16% of group vv1. A significant difference in frequency of finding (c) was obtained between groups vv1 and vv0. The positive and negative predictive values of finding (c) were 66.7% and 77.9%, respectively. Conclusion: Findings (b) and (c), especially the latter, may partly contribute to the radiological diagnosis of minute HVI.

AB - Purpose: The aim of this study was to elucidate computed tomography hepatic arteriography (CTHA) and CT arterial portography (CTAP) findings characteristic of hepatocellular carcinoma (HCC) with large hepatic venous invasion (HVI) and then to examine whether the presence of minute HVI can be diagnosed based on each finding. Materials and methods: Combined CTHA and CTAP of 106 HCCs were examined. Two radiologists analyzed the radiological findings of five nodules with large HVI (group vv2). The remaining 101 nodules were classified into two groups: group vv1, positive minute HVI; group vv0, negative HVI. They examined whether each finding observed in group vv2 could be detected in groups vv1 and vv0. Results: Analysis of group vv2 identified (a) tumor thrombus, (b) early inflow of the contrast into the hepatic vein proximal to the invaded site, and (c) partially decreased portal venous flow in the peripheral parenchyma subject to the involved hepatic vein. Findings (b) and (c) were observed in 16% of group vv1. A significant difference in frequency of finding (c) was obtained between groups vv1 and vv0. The positive and negative predictive values of finding (c) were 66.7% and 77.9%, respectively. Conclusion: Findings (b) and (c), especially the latter, may partly contribute to the radiological diagnosis of minute HVI.

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