Real-Time 3-Dimensional Virtual Reality Navigation System with Open MRI for Breast-Conserving Surgery

Morimasa Tomikawa, Jaesung Hong, Satoko Shiotani, Eriko Tokunaga, Kozo Konishi, Satoshi Ieiri, Kazuo Tanoue, Tomohiko Akahoshi, Yoshihiko Maehara, Makoto Hashizume

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

抄録

Background: The aim of this study was to report on the early experiences using a real-time 3-dimensional (3D) virtual reality navigation system with open MRI for breast-conserving surgery. Study Design: We developed a real-time 3D virtual reality navigation system with open MRI, and evaluated the mismatch between the navigation system and real distance using a 3D phantom. Two patients with nonpalpable MRI-detected breast tumors underwent breast-conserving surgery under the guidance of the navigation system. An initial MRI for the breast tumor using skin-affixed markers was performed immediately before excision. A percutaneous intramammary dye marker was applied to delineate an excision line, and the computer software "3D Slicer" generated a real-time 3D virtual reality model of the tumor and the puncture needle in the breast. Excision of the tumor was performed in the usual manner along the excision line indicated with the dye. The resected specimens were carefully examined histopathologically. Results: The mean mismatch between the navigation system and real distance was 2.01 ± 0.32 mm when evaluated with the 3D phantom. Under guidance by the navigation system, a percutaneous intramammary dye marker was applied without any difficulty. Fiducial registration errors were 3.00 mm for patient no. 1, and 4.07 mm for patient no. 2. Histopathological examinations of the resected specimens of the 2 patients showed noninvasive ductal carcinoma in situ. The surgical margins were free of carcinoma cells. Conclusions: Real-time 3D virtual reality navigation system with open MRI is feasible for safe and accurate excision of nonpalpable MRI-detected breast tumors. Long-term outcomes of this technique should be evaluated further.

元の言語英語
ページ(範囲)927-933
ページ数7
ジャーナルJournal of the American College of Surgeons
210
発行部数6
DOI
出版物ステータス出版済み - 6 1 2010

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Segmental Mastectomy
Coloring Agents
Breast Neoplasms
Carcinoma, Intraductal, Noninfiltrating
Punctures
Needles
Neoplasms
Breast
Software
Carcinoma
Skin

All Science Journal Classification (ASJC) codes

  • Surgery

これを引用

Real-Time 3-Dimensional Virtual Reality Navigation System with Open MRI for Breast-Conserving Surgery. / Tomikawa, Morimasa; Hong, Jaesung; Shiotani, Satoko; Tokunaga, Eriko; Konishi, Kozo; Ieiri, Satoshi; Tanoue, Kazuo; Akahoshi, Tomohiko; Maehara, Yoshihiko; Hashizume, Makoto.

:: Journal of the American College of Surgeons, 巻 210, 番号 6, 01.06.2010, p. 927-933.

研究成果: ジャーナルへの寄稿記事

Tomikawa, M, Hong, J, Shiotani, S, Tokunaga, E, Konishi, K, Ieiri, S, Tanoue, K, Akahoshi, T, Maehara, Y & Hashizume, M 2010, 'Real-Time 3-Dimensional Virtual Reality Navigation System with Open MRI for Breast-Conserving Surgery', Journal of the American College of Surgeons, 巻. 210, 番号 6, pp. 927-933. https://doi.org/10.1016/j.jamcollsurg.2010.01.032
Tomikawa, Morimasa ; Hong, Jaesung ; Shiotani, Satoko ; Tokunaga, Eriko ; Konishi, Kozo ; Ieiri, Satoshi ; Tanoue, Kazuo ; Akahoshi, Tomohiko ; Maehara, Yoshihiko ; Hashizume, Makoto. / Real-Time 3-Dimensional Virtual Reality Navigation System with Open MRI for Breast-Conserving Surgery. :: Journal of the American College of Surgeons. 2010 ; 巻 210, 番号 6. pp. 927-933.
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abstract = "Background: The aim of this study was to report on the early experiences using a real-time 3-dimensional (3D) virtual reality navigation system with open MRI for breast-conserving surgery. Study Design: We developed a real-time 3D virtual reality navigation system with open MRI, and evaluated the mismatch between the navigation system and real distance using a 3D phantom. Two patients with nonpalpable MRI-detected breast tumors underwent breast-conserving surgery under the guidance of the navigation system. An initial MRI for the breast tumor using skin-affixed markers was performed immediately before excision. A percutaneous intramammary dye marker was applied to delineate an excision line, and the computer software {"}3D Slicer{"} generated a real-time 3D virtual reality model of the tumor and the puncture needle in the breast. Excision of the tumor was performed in the usual manner along the excision line indicated with the dye. The resected specimens were carefully examined histopathologically. Results: The mean mismatch between the navigation system and real distance was 2.01 ± 0.32 mm when evaluated with the 3D phantom. Under guidance by the navigation system, a percutaneous intramammary dye marker was applied without any difficulty. Fiducial registration errors were 3.00 mm for patient no. 1, and 4.07 mm for patient no. 2. Histopathological examinations of the resected specimens of the 2 patients showed noninvasive ductal carcinoma in situ. The surgical margins were free of carcinoma cells. Conclusions: Real-time 3D virtual reality navigation system with open MRI is feasible for safe and accurate excision of nonpalpable MRI-detected breast tumors. Long-term outcomes of this technique should be evaluated further.",
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AU - Tomikawa, Morimasa

AU - Hong, Jaesung

AU - Shiotani, Satoko

AU - Tokunaga, Eriko

AU - Konishi, Kozo

AU - Ieiri, Satoshi

AU - Tanoue, Kazuo

AU - Akahoshi, Tomohiko

AU - Maehara, Yoshihiko

AU - Hashizume, Makoto

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N2 - Background: The aim of this study was to report on the early experiences using a real-time 3-dimensional (3D) virtual reality navigation system with open MRI for breast-conserving surgery. Study Design: We developed a real-time 3D virtual reality navigation system with open MRI, and evaluated the mismatch between the navigation system and real distance using a 3D phantom. Two patients with nonpalpable MRI-detected breast tumors underwent breast-conserving surgery under the guidance of the navigation system. An initial MRI for the breast tumor using skin-affixed markers was performed immediately before excision. A percutaneous intramammary dye marker was applied to delineate an excision line, and the computer software "3D Slicer" generated a real-time 3D virtual reality model of the tumor and the puncture needle in the breast. Excision of the tumor was performed in the usual manner along the excision line indicated with the dye. The resected specimens were carefully examined histopathologically. Results: The mean mismatch between the navigation system and real distance was 2.01 ± 0.32 mm when evaluated with the 3D phantom. Under guidance by the navigation system, a percutaneous intramammary dye marker was applied without any difficulty. Fiducial registration errors were 3.00 mm for patient no. 1, and 4.07 mm for patient no. 2. Histopathological examinations of the resected specimens of the 2 patients showed noninvasive ductal carcinoma in situ. The surgical margins were free of carcinoma cells. Conclusions: Real-time 3D virtual reality navigation system with open MRI is feasible for safe and accurate excision of nonpalpable MRI-detected breast tumors. Long-term outcomes of this technique should be evaluated further.

AB - Background: The aim of this study was to report on the early experiences using a real-time 3-dimensional (3D) virtual reality navigation system with open MRI for breast-conserving surgery. Study Design: We developed a real-time 3D virtual reality navigation system with open MRI, and evaluated the mismatch between the navigation system and real distance using a 3D phantom. Two patients with nonpalpable MRI-detected breast tumors underwent breast-conserving surgery under the guidance of the navigation system. An initial MRI for the breast tumor using skin-affixed markers was performed immediately before excision. A percutaneous intramammary dye marker was applied to delineate an excision line, and the computer software "3D Slicer" generated a real-time 3D virtual reality model of the tumor and the puncture needle in the breast. Excision of the tumor was performed in the usual manner along the excision line indicated with the dye. The resected specimens were carefully examined histopathologically. Results: The mean mismatch between the navigation system and real distance was 2.01 ± 0.32 mm when evaluated with the 3D phantom. Under guidance by the navigation system, a percutaneous intramammary dye marker was applied without any difficulty. Fiducial registration errors were 3.00 mm for patient no. 1, and 4.07 mm for patient no. 2. Histopathological examinations of the resected specimens of the 2 patients showed noninvasive ductal carcinoma in situ. The surgical margins were free of carcinoma cells. Conclusions: Real-time 3D virtual reality navigation system with open MRI is feasible for safe and accurate excision of nonpalpable MRI-detected breast tumors. Long-term outcomes of this technique should be evaluated further.

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