Recent advances and patents on circulatory support devices for pediatric patients

Akira Shiose, Kiyotaka Fukamachi

研究成果: ジャーナルへの寄稿記事

抄録

Recent progress in medical management has significantly improved the range of treatments for children with severe heart failure; however, some patients still suffer from refractory heart failure, necessitating heart transplantation. Transplantation is the definitive therapy for end-stage heart failure in children and adults; however, many patients die before transplantation because of the shortage of donor organs. Mechanical circulatory support devices have offered new treatment options for these patients. For many years, extracorporeal membrane oxygenation (ECMO) has served as the main circulatory assist device for children. However, long-term support with ECMO is not recommended because of the accompanying severe complications, such as cerebral infarction, brain hemorrhage, and renal and multiorgan failure. The development of ventricular assist devices specifically for children is lagging behind efforts aimed at treating adults. Furthermore, a total artificial heart is not thought suitable for children because of their growth rate. The National Heart, Lung, and Blood Institute has supported efforts to develop pediatric-specific devices at five institutions in the United States since 2004. There are only a few patents for circulatory support devices designed for pediatric patients, and there is still much room to improve currently available pediatric circulatory devices.

元の言語英語
ページ(範囲)161-164
ページ数4
ジャーナルRecent Patents on Biomedical Engineering
2
発行部数3
DOI
出版物ステータス出版済み - 11 2009
外部発表Yes

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Pediatrics
Patents
Equipment and Supplies
Extracorporeal Membrane Oxygenation
Oxygenation
Heart Failure
Transplantation
Artificial heart
National Heart, Lung, and Blood Institute (U.S.)
Membranes
Artificial Heart
Heart-Assist Devices
Cerebral Infarction
Cerebral Hemorrhage
Heart Transplantation
Refractory materials
Renal Insufficiency
Brain
Blood
Therapeutics

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering

これを引用

Recent advances and patents on circulatory support devices for pediatric patients. / Shiose, Akira; Fukamachi, Kiyotaka.

:: Recent Patents on Biomedical Engineering, 巻 2, 番号 3, 11.2009, p. 161-164.

研究成果: ジャーナルへの寄稿記事

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