Recent advances in the pathogenesis of hyper IgE syndrome

Hidetoshi Takada, Yoshiyuki Minegishi

研究成果: Contribution to journalReview article査読

1 被引用数 (Scopus)

抄録

Hyperimmunoglobulin-E syndrome (HIES) is one of the primary immunodeficiency with the manifestations of recurrent infections especially with Staphylococcus aureus, characteristic facies, hyperextensibility of joints, multiple bone fractures, scoliosis, and delayed shedding of the primary teeth. It is a multisystem disease of autosomal dominant or recessive inheritance. Recently, the genetic causes of HIES (STAT3, TYK2, and DOCK8) were clarified.

本文言語英語
ページ(範囲)15-19
ページ数5
ジャーナルJapanese Journal of Clinical Immunology
33
1
DOI
出版ステータス出版済み - 2010

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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