Recent strategic advances for the activation of benzylic C–H bonds for the formation of C–C bonds

研究成果: Contribution to journalReview article

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Alkylarenes, obtained from abundant hydrocarbon feedstock sources, are an attractive starting material for the formation of complex molecular architectures. Conventional activation strategies of the relatively inert sp3-hybridized benzylic C–H bonds usually require relatively harsh conditions and are difficult to apply to the synthesis of fine chemicals. The present review describes recent strategic advances for the activation of benzylic C–H bonds for the catalytic formation of C–C bonds. In particular, two activation methods, i.e., strategies that generate benzylic radicals or benzyl anions, are discussed.

元の言語英語
記事番号151225
ジャーナルTetrahedron Letters
60
発行部数45
DOI
出版物ステータス出版済み - 11 7 2019

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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