Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer

Pamela S. Ohashi, Tak W. Mak, Peter Van Den Elsen, Yusuke Yanagi, Yasunobu Yoshikai, Andrew F. Calman, Cox Terhorst, John D. Stobo, Arthur Weiss

    研究成果: ジャーナルへの寄稿記事

    187 引用 (Scopus)

    抄録

    We have introduced a full-length complementary DNA of the T-cell antigen receptor β-chain into a mutant human T-cell line that lacked a complete β-chain messenger RNA, had a diminished level of α-chain transcript and did not express surface T3- or antigen receptor. Expression of the transfected β-chain led to a normal level of α-chain transcript and a structurally and functionally active T3 T-cell antigen receptor complex on the cell surface.

    元の言語英語
    ページ(範囲)606-609
    ページ数4
    ジャーナルNature
    316
    発行部数6029
    DOI
    出版物ステータス出版済み - 12 1 1985

    Fingerprint

    CD3 Antigens
    T-Cell Antigen Receptor
    Thyroid Hormone Receptors
    Antigen Receptors
    DNA
    Surface Antigens
    Complementary DNA
    T-Lymphocytes
    Cell Line
    Messenger RNA

    All Science Journal Classification (ASJC) codes

    • Medicine(all)
    • General

    これを引用

    Ohashi, P. S., Mak, T. W., Van Den Elsen, P., Yanagi, Y., Yoshikai, Y., Calman, A. F., ... Weiss, A. (1985). Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. Nature, 316(6029), 606-609. https://doi.org/10.1038/316606a0

    Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. / Ohashi, Pamela S.; Mak, Tak W.; Van Den Elsen, Peter; Yanagi, Yusuke; Yoshikai, Yasunobu; Calman, Andrew F.; Terhorst, Cox; Stobo, John D.; Weiss, Arthur.

    :: Nature, 巻 316, 番号 6029, 01.12.1985, p. 606-609.

    研究成果: ジャーナルへの寄稿記事

    Ohashi, PS, Mak, TW, Van Den Elsen, P, Yanagi, Y, Yoshikai, Y, Calman, AF, Terhorst, C, Stobo, JD & Weiss, A 1985, 'Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer', Nature, 巻. 316, 番号 6029, pp. 606-609. https://doi.org/10.1038/316606a0
    Ohashi PS, Mak TW, Van Den Elsen P, Yanagi Y, Yoshikai Y, Calman AF その他. Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. Nature. 1985 12 1;316(6029):606-609. https://doi.org/10.1038/316606a0
    Ohashi, Pamela S. ; Mak, Tak W. ; Van Den Elsen, Peter ; Yanagi, Yusuke ; Yoshikai, Yasunobu ; Calman, Andrew F. ; Terhorst, Cox ; Stobo, John D. ; Weiss, Arthur. / Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. :: Nature. 1985 ; 巻 316, 番号 6029. pp. 606-609.
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    AU - Yoshikai, Yasunobu

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    AU - Terhorst, Cox

    AU - Stobo, John D.

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