Reduction of antides to amines via catalytic hydrosilylation by a rhodium complex

Ryoichi Kuwano, Masatoshi Takahashi, Yoshihiko Ito

研究成果: ジャーナルへの寄稿記事

140 引用 (Scopus)

抜粋

Reduction of a wide range of tertiary amides with 2 molar equivalents of diphenylsilane was promoted by 0.1 mol% of RhH(CO)(PPh3)3 at room temperature, affording the corresponding tertiary amines in high yields. The synthetic utility is demonstrated by chemoselective reductions of amides having functional groups such as ester and epoxy groups which are not tolerated by the conventional reductions with LiAlH4 and BH3.

元の言語英語
ページ(範囲)1017-1020
ページ数4
ジャーナルTetrahedron Letters
39
発行部数9
DOI
出版物ステータス出版済み - 2 26 1998
外部発表Yes

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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