Reduction of the magnetic signal from unbound magnetic markers for magnetic immunoassay without bound/free separation

A. Tsukamoto, H. Kuma, K. Saitoh, A. Kandori, K. Yoshinaga, Y. Sugiura, N. Hamasaki, Keiji Enpuku

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

抄録

We investigated the effect of adding magnetic shielding and applying of a compensation field to reduce the magnetic signal from unbound free markers. When the initial immunoassay system was used without the additional shielding box, the signal intensity of the liquid markers normalized by the weight of the Fe3O4 was 1/2700 of the dried markers. By installing the additional shielding box, the reduction factor was improved to 1/10,000. We successfully reduced the magnetic signal of the liquid marker further by applying a compensation field. The magnetic signal of the free marker obtained by applying a compensation field of -18 nT was 1.4 mΦ0, which was close to the system noise level. Field compensation at the very local area just around the SQUID is sufficient for reducing of the magnetic signal from the free marker.

元の言語英語
ページ(範囲)1024-1028
ページ数5
ジャーナルPhysica C: Superconductivity and its applications
463-465
発行部数SUPPL.
DOI
出版物ステータス出版済み - 10 1 2007

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magnetic signals
immunoassay
markers
Shielding
Magnetic shielding
shielding
boxes
SQUIDs
Liquids
magnetic shielding
liquids
installing
Compensation and Redress

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Energy Engineering and Power Technology
  • Electrical and Electronic Engineering

これを引用

Reduction of the magnetic signal from unbound magnetic markers for magnetic immunoassay without bound/free separation. / Tsukamoto, A.; Kuma, H.; Saitoh, K.; Kandori, A.; Yoshinaga, K.; Sugiura, Y.; Hamasaki, N.; Enpuku, Keiji.

:: Physica C: Superconductivity and its applications, 巻 463-465, 番号 SUPPL., 01.10.2007, p. 1024-1028.

研究成果: ジャーナルへの寄稿記事

Tsukamoto, A, Kuma, H, Saitoh, K, Kandori, A, Yoshinaga, K, Sugiura, Y, Hamasaki, N & Enpuku, K 2007, 'Reduction of the magnetic signal from unbound magnetic markers for magnetic immunoassay without bound/free separation', Physica C: Superconductivity and its applications, 巻. 463-465, 番号 SUPPL., pp. 1024-1028. https://doi.org/10.1016/j.physc.2007.04.284
Tsukamoto, A. ; Kuma, H. ; Saitoh, K. ; Kandori, A. ; Yoshinaga, K. ; Sugiura, Y. ; Hamasaki, N. ; Enpuku, Keiji. / Reduction of the magnetic signal from unbound magnetic markers for magnetic immunoassay without bound/free separation. :: Physica C: Superconductivity and its applications. 2007 ; 巻 463-465, 番号 SUPPL. pp. 1024-1028.
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AU - Sugiura, Y.

AU - Hamasaki, N.

AU - Enpuku, Keiji

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