Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED)

a promising new treatment in pediatric surgery

Tomoaki Taguchi, Yusuke Yanagi, Koichiro Yoshimaru, Xiu Ying Zhang, Toshiharu Matsuura, Koichi Nakayama, Eiji Kobayashi, Haruyoshi Yamaza, Kazuaki Nonaka, Shoichi Ohga, Takayoshi Yamaza

研究成果: ジャーナルへの寄稿評論記事

抄録

Stem cells from human exfoliated deciduous teeth (SHEDs), being a type of mesenchymal stem cell, are an ideal cell source for regenerative medicine. They have minimal risk of oncogenesis, high proliferative capacity, high multipotency, and immunosuppressive ability. Stem cell transplantation using SHED has been found to have an anti-fibrotic effect on liver fibrosis in mice. SHED transplantation and the bio 3D printer, which can create scaffold-free 3-D images of the liver and diaphragm, provide a new innovative treatment modality for intractable pediatric surgical diseases such as biliary atresia and diaphragmatic hernia.

元の言語英語
ページ(範囲)316-322
ページ数7
ジャーナルSurgery today
49
発行部数4
DOI
出版物ステータス出版済み - 4 10 2019

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Biliary Atresia
Diaphragmatic Hernia
Regenerative Medicine
Deciduous Tooth
Three-Dimensional Imaging
Stem Cell Transplantation
Immunosuppressive Agents
Diaphragm
Mesenchymal Stromal Cells
Liver Cirrhosis
Carcinogenesis
Stem Cells
Transplantation
Pediatrics
Liver
Therapeutics
Three Dimensional Printing

All Science Journal Classification (ASJC) codes

  • Surgery

これを引用

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title = "Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED): a promising new treatment in pediatric surgery",
abstract = "Stem cells from human exfoliated deciduous teeth (SHEDs), being a type of mesenchymal stem cell, are an ideal cell source for regenerative medicine. They have minimal risk of oncogenesis, high proliferative capacity, high multipotency, and immunosuppressive ability. Stem cell transplantation using SHED has been found to have an anti-fibrotic effect on liver fibrosis in mice. SHED transplantation and the bio 3D printer, which can create scaffold-free 3-D images of the liver and diaphragm, provide a new innovative treatment modality for intractable pediatric surgical diseases such as biliary atresia and diaphragmatic hernia.",
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AU - Taguchi, Tomoaki

AU - Yanagi, Yusuke

AU - Yoshimaru, Koichiro

AU - Zhang, Xiu Ying

AU - Matsuura, Toshiharu

AU - Nakayama, Koichi

AU - Kobayashi, Eiji

AU - Yamaza, Haruyoshi

AU - Nonaka, Kazuaki

AU - Ohga, Shoichi

AU - Yamaza, Takayoshi

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