Registration between histopathological images with different stains and an MRI Image of pancreatic cancer tumor

Hidekata Hontani, Yushi Goto, Yuki Tamura, Tomoshige Shimomura, Naoki Kawamura, Hirokazu Kobayashi, Mauricio Kugler, Tatsuya Yokota, Chika Iwamoto, Kenoki Ouchida, Makoto Hashizume, Takahiro Katagiri, Tomonari Sei, Akinobu Shimizu

研究成果: 著書/レポートタイプへの貢献会議での発言

抄録

In this paper, we report on the construction of a pancreatic tumor model that represents the relationship between the tumor growth and the micro anatomical structures. The former, the tumor growth, is described by referring to the temporal series of MRI images of the whole body and the latter, the micro structures of the tumor, is described by a spatial series of microscopic images of thin-sections sliced from the extracted pancreatic tumor. For the model construction, we developed new non-rigid registration methods for (1) accurate description of tumor growth, (2) reconstruction of 3D microscopic images, and (3) registration between an MRI image and corresponding microscopic images. In addition, we constructed a neural network that can generate a set of fake microscopic image patches of a pancreatic tumor that corresponds to each voxel inside the tumor region in an MRI image. The outlines of the methods are introduced and some examples of experimental results are demonstrated.

元の言語英語
ホスト出版物のタイトルInternational Forum on Medical Imaging in Asia 2019
編集者Hiroshi Fujita, Jong Hyo Kim, Feng Lin
出版者SPIE
ISBN(電子版)9781510627758
DOI
出版物ステータス出版済み - 1 1 2019
イベントInternational Forum on Medical Imaging in Asia 2019 - Singapore, シンガポール
継続期間: 1 7 20191 9 2019

出版物シリーズ

名前Proceedings of SPIE - The International Society for Optical Engineering
11050
ISSN(印刷物)0277-786X
ISSN(電子版)1996-756X

会議

会議International Forum on Medical Imaging in Asia 2019
シンガポール
Singapore
期間1/7/191/9/19

Fingerprint

Magnetic resonance imaging
Registration
Tumors
Tumor
Cancer
Coloring Agents
tumors
cancer
Tumor Growth
Non-rigid Registration
Series
Voxel
3D Image
microstructure
Microstructure
Patch
Neural Networks
Experimental Results
Neural networks
Model

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

これを引用

Hontani, H., Goto, Y., Tamura, Y., Shimomura, T., Kawamura, N., Kobayashi, H., ... Shimizu, A. (2019). Registration between histopathological images with different stains and an MRI Image of pancreatic cancer tumor. : H. Fujita, J. H. Kim, & F. Lin (版), International Forum on Medical Imaging in Asia 2019 [110501F] (Proceedings of SPIE - The International Society for Optical Engineering; 巻数 11050). SPIE. https://doi.org/10.1117/12.2522052

Registration between histopathological images with different stains and an MRI Image of pancreatic cancer tumor. / Hontani, Hidekata; Goto, Yushi; Tamura, Yuki; Shimomura, Tomoshige; Kawamura, Naoki; Kobayashi, Hirokazu; Kugler, Mauricio; Yokota, Tatsuya; Iwamoto, Chika; Ouchida, Kenoki; Hashizume, Makoto; Katagiri, Takahiro; Sei, Tomonari; Shimizu, Akinobu.

International Forum on Medical Imaging in Asia 2019. 版 / Hiroshi Fujita; Jong Hyo Kim; Feng Lin. SPIE, 2019. 110501F (Proceedings of SPIE - The International Society for Optical Engineering; 巻 11050).

研究成果: 著書/レポートタイプへの貢献会議での発言

Hontani, H, Goto, Y, Tamura, Y, Shimomura, T, Kawamura, N, Kobayashi, H, Kugler, M, Yokota, T, Iwamoto, C, Ouchida, K, Hashizume, M, Katagiri, T, Sei, T & Shimizu, A 2019, Registration between histopathological images with different stains and an MRI Image of pancreatic cancer tumor. : H Fujita, JH Kim & F Lin (版), International Forum on Medical Imaging in Asia 2019., 110501F, Proceedings of SPIE - The International Society for Optical Engineering, 巻. 11050, SPIE, International Forum on Medical Imaging in Asia 2019, Singapore, シンガポール, 1/7/19. https://doi.org/10.1117/12.2522052
Hontani H, Goto Y, Tamura Y, Shimomura T, Kawamura N, Kobayashi H その他. Registration between histopathological images with different stains and an MRI Image of pancreatic cancer tumor. : Fujita H, Kim JH, Lin F, 編集者, International Forum on Medical Imaging in Asia 2019. SPIE. 2019. 110501F. (Proceedings of SPIE - The International Society for Optical Engineering). https://doi.org/10.1117/12.2522052
Hontani, Hidekata ; Goto, Yushi ; Tamura, Yuki ; Shimomura, Tomoshige ; Kawamura, Naoki ; Kobayashi, Hirokazu ; Kugler, Mauricio ; Yokota, Tatsuya ; Iwamoto, Chika ; Ouchida, Kenoki ; Hashizume, Makoto ; Katagiri, Takahiro ; Sei, Tomonari ; Shimizu, Akinobu. / Registration between histopathological images with different stains and an MRI Image of pancreatic cancer tumor. International Forum on Medical Imaging in Asia 2019. 編集者 / Hiroshi Fujita ; Jong Hyo Kim ; Feng Lin. SPIE, 2019. (Proceedings of SPIE - The International Society for Optical Engineering).
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AU - Kobayashi, Hirokazu

AU - Kugler, Mauricio

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AU - Iwamoto, Chika

AU - Ouchida, Kenoki

AU - Hashizume, Makoto

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