Regulation of microtubule dynamics by kinesins

研究成果: Contribution to journalReview article査読

31 被引用数 (Scopus)

抄録

The simple mechanistic and functional division of the kinesin family into either active translocators or non-motile microtubule depolymerases was initially appropriate but is now proving increasingly unhelpful, given evidence that several translocase kinesins can affect microtubule dynamics, whilst non-translocase kinesins can promote microtubule assembly and depolymerisation. Such multi-role kinesins act either directly on microtubule dynamics, by interaction with microtubules and tubulin, or indirectly, through the transport of other factors along the lattice to the microtubule tip. Here I review recent progress on the mechanisms and roles of these translocase kinesins.

本文言語英語
ページ(範囲)927-934
ページ数8
ジャーナルSeminars in Cell and Developmental Biology
22
9
DOI
出版ステータス出版済み - 12 2011
外部発表はい

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Cell Biology

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