Regulation of spermatogonial stem cell compartment in the mouse testis.

研究成果: ジャーナルへの寄稿評論記事

2 引用 (Scopus)

抄録

Spermatogenesis occurs throughout the adult lifetime of males and is supported by a robust stem cell system. Spermatogonial stem cells (SSCs) are the stem cells of postnatal male germ cells, and not only self-renew but also produce differentiated progeny continuously. Recent report revealed that differentiating spermatogonia could revert into an undifferentiated state, although it was believed that SSCs were homogeneous and that differentiating spermatogonia was not reversible. Although several molecules, which regulate SSC, have been identified so far, molecular mechanisms underlying the maintenance of SSCs as well as the reversible developmental lineage of SSCs remain to be elucidated. In this review, we describe a brief overview of spermatogenesis and summarize the molecular regulation of SSC compartment.

元の言語英語
ページ(範囲)1-10
ページ数10
ジャーナルFukuoka igaku zasshi = Hukuoka acta medica
105
発行部数1
出版物ステータス出版済み - 1 2014

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Testis
Stem Cells
Spermatogonia
Spermatogenesis
Germ Cells
Maintenance

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Regulation of spermatogonial stem cell compartment in the mouse testis. / Iwamori, Naoki.

:: Fukuoka igaku zasshi = Hukuoka acta medica, 巻 105, 番号 1, 01.2014, p. 1-10.

研究成果: ジャーナルへの寄稿評論記事

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