Relation between bactericidal and phagocytic activities of peritoneal macrophages induced by irritants

S. Miake, K. Takeya, T. Matsumoto, Y. Yoshikai, K. Nomoto

    研究成果: Contribution to journalArticle査読

    3 被引用数 (Scopus)

    抄録

    Bactericidal activity against Listeria monocytogenes and phagocytic function against sheep red blood cells (SRBC) were studied in mice to which various irritants were given i.p. Although thioglycollate-induced macrophages phagocytosed native SRBC, their bactericidal capacity was poor compared with that of normal resident macrophages. Corynebacterium parvum-induced macrophages, however, effectively inhibited the growth of Listeria and exhibited strong phagocytic activity against SRBC. It was suggested that free macrophages accumulating in the induced inflammatory region had different functional activities depending on irritants used.

    本文言語英語
    ページ(範囲)421-427
    ページ数7
    ジャーナルRES Journal of the Reticuloendothelial Society
    27
    4
    出版ステータス出版済み - 1980

    All Science Journal Classification (ASJC) codes

    • 血液学

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