Relationship between Nisin Z Fermentative Production and Aeration Condition Using Lactococcus lactis IO-1

Noppawan Chinachoti, Tomoko Zaima, Hiromi Matsusaki, Kenji Sonomoto, Ayaaki Ishizaki

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)


Lactococcus lactis IO-1 produces a peptide antibiotic, nisin Z by using glucose as well as xylose as a carbon source. To investigate the relationship between nisin Z production and aeration condition for the fermentation, fermentation was run in flask and jar fermenter with xylose and glucose. Optimal aeration condition for nisin Z production was not always that for cell growth and lactate production. The influence of aeration on nisin Z production was observed highly severe in flask-based fermentation because of uncontrolled pH condition even in the presence of CaCO3. Degradation of nisin Z produced was scarcely observed under the optimized conditions for aeration, which might give less expression of the activities of the degrading enzymes.

ジャーナルJournal of the Faculty of Agriculture, Kyushu University
出版物ステータス出版済み - 3 1 1998


All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Agronomy and Crop Science