Relationship between non-specific activity of macrophages and immune responses to Listeria monocytogenes

Yasunobu Yoshikai, S. Miake, T. Matsumoto, K. Nomoto, K. Takeya

    研究成果: ジャーナルへの寄稿記事

    17 引用 (Scopus)

    抄録

    Delayed footpad reactions and acquired cellular resistance to Listeria monocytogenes were studied in mice whose mononuclear phagocyte system (MPS) had been blocked or stimulated. Colloidal carbon was used for the blockade of MPS and Corynebacterium parvum used for the stimulation. Strong delayed footpad reactions. On the other hand, the i.v. injection of 3 x 10 1 listeria induced an appreciable level mice, while in MPS-stimulated mice, i.v. injection with even 4 x 10 3 listeria could not induce such strong delayed footpad reaction. On the other hand, the i.v. injection of 3 x 10 1 listeria induced an appreciable level of delayed footpad reaction only in MPS-blocked mice. Acquired cellular resistance was depressed by MPS stimulation, whereas it was augmented by MPS blockade. These results suggested that non-specific activity of MPS modulates subsequent immune responses after inoculation of listeria.

    元の言語英語
    ページ(範囲)295-301
    ページ数7
    ジャーナルImmunology
    40
    発行部数3
    出版物ステータス出版済み - 9 19 1980

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    Mononuclear Phagocyte System
    Listeria monocytogenes
    Macrophages
    Listeria
    Injections
    Propionibacterium acnes
    Carbon

    All Science Journal Classification (ASJC) codes

    • Immunology and Allergy
    • Immunology

    これを引用

    Yoshikai, Y., Miake, S., Matsumoto, T., Nomoto, K., & Takeya, K. (1980). Relationship between non-specific activity of macrophages and immune responses to Listeria monocytogenes. Immunology, 40(3), 295-301.

    Relationship between non-specific activity of macrophages and immune responses to Listeria monocytogenes. / Yoshikai, Yasunobu; Miake, S.; Matsumoto, T.; Nomoto, K.; Takeya, K.

    :: Immunology, 巻 40, 番号 3, 19.09.1980, p. 295-301.

    研究成果: ジャーナルへの寄稿記事

    Yoshikai, Y, Miake, S, Matsumoto, T, Nomoto, K & Takeya, K 1980, 'Relationship between non-specific activity of macrophages and immune responses to Listeria monocytogenes', Immunology, 巻. 40, 番号 3, pp. 295-301.
    Yoshikai Y, Miake S, Matsumoto T, Nomoto K, Takeya K. Relationship between non-specific activity of macrophages and immune responses to Listeria monocytogenes. Immunology. 1980 9 19;40(3):295-301.
    Yoshikai, Yasunobu ; Miake, S. ; Matsumoto, T. ; Nomoto, K. ; Takeya, K. / Relationship between non-specific activity of macrophages and immune responses to Listeria monocytogenes. :: Immunology. 1980 ; 巻 40, 番号 3. pp. 295-301.
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    abstract = "Delayed footpad reactions and acquired cellular resistance to Listeria monocytogenes were studied in mice whose mononuclear phagocyte system (MPS) had been blocked or stimulated. Colloidal carbon was used for the blockade of MPS and Corynebacterium parvum used for the stimulation. Strong delayed footpad reactions. On the other hand, the i.v. injection of 3 x 10 1 listeria induced an appreciable level mice, while in MPS-stimulated mice, i.v. injection with even 4 x 10 3 listeria could not induce such strong delayed footpad reaction. On the other hand, the i.v. injection of 3 x 10 1 listeria induced an appreciable level of delayed footpad reaction only in MPS-blocked mice. Acquired cellular resistance was depressed by MPS stimulation, whereas it was augmented by MPS blockade. These results suggested that non-specific activity of MPS modulates subsequent immune responses after inoculation of listeria.",
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    AU - Yoshikai, Yasunobu

    AU - Miake, S.

    AU - Matsumoto, T.

    AU - Nomoto, K.

    AU - Takeya, K.

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    N2 - Delayed footpad reactions and acquired cellular resistance to Listeria monocytogenes were studied in mice whose mononuclear phagocyte system (MPS) had been blocked or stimulated. Colloidal carbon was used for the blockade of MPS and Corynebacterium parvum used for the stimulation. Strong delayed footpad reactions. On the other hand, the i.v. injection of 3 x 10 1 listeria induced an appreciable level mice, while in MPS-stimulated mice, i.v. injection with even 4 x 10 3 listeria could not induce such strong delayed footpad reaction. On the other hand, the i.v. injection of 3 x 10 1 listeria induced an appreciable level of delayed footpad reaction only in MPS-blocked mice. Acquired cellular resistance was depressed by MPS stimulation, whereas it was augmented by MPS blockade. These results suggested that non-specific activity of MPS modulates subsequent immune responses after inoculation of listeria.

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