Relationship between phagocytic activity of macrophages and delayed footpad reaction against syngeneic testicular cells

K. Nomoto, Y. Yoshikai, S. Yoshida, S. Miake

    研究成果: Contribution to journalArticle査読

    2 被引用数 (Scopus)

    抄録

    The delayed footpad reaction against syngeneic testicular cells was studied in cyclophosphamide (CY)-pretreated mice whose mononuclear phagocyte system (MPS) was blocked with colloidal carbon or stimulated with Corynebacterium parvum (C. parvum). The delayed footpad reaction was augmented by MPS-blockade, whereas it was depressed by MPS-stimulation. It was observed that syngeneic testicular cells were phagocytized and degraded more effectively by C. parvum-stimulated macrophages in vitro and that the testicular antigen phagocytized by C. parvum-stimulated macrophages proved to become less immunogenic in cell transfer experiments.

    本文言語英語
    ページ(範囲)141-146
    ページ数6
    ジャーナルJournal of Clinical and Laboratory Immunology
    7
    2
    出版ステータス出版済み - 1982

    All Science Journal Classification (ASJC) codes

    • 免疫学

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