TY - GEN
T1 - Relationship between pulse number of rTMS and inter reversal time of perceptual reversal
AU - Nojima, K.
AU - Ge, S.
AU - Katayama, Y.
AU - Iramina, K.
PY - 2011
Y1 - 2011
N2 - The aim of this study is to investigate the stimulus parameter which affects the repetitive Transcranial Magnetic Stimulation (rTMS) effect. It is said that the condition under 1Hz rTMS induces the inhibition effect. On the other hand, the condition over 1Hz rTMS induces the facilitation effect. However the number of pulses of rTMS is also important factor. In this study, we focused on the number of pulses. We used the cognitive task of perceptual reversal and compared the rTMS effects of different condition under 1Hz which is the inhibition condition. It has been known that the right superior parietal lobule (SPL) has a role in perceptual reversal. We applied rTMS over the SPL and measured the inter-reversal time (IRT) of perceptual reversal. The results showed that when 0.25Hz 60pulses, 0.5Hz 60pulses and 1Hz 60pulses of rTMS was applied over the right SPL, the IRT was significantly smaller. On the other hand, when 1Hz 240pulses of rTMS was applied over the right SPL, the IRT was significantly longer. When 0.25Hz 120pulses, 0.5Hz 120pulses and 1Hz 120pulses of rTMS was applied over the right SPL, there were no significant differences. Furthermore, to investigate the rTMS effects, when rTMS are applied over the motor area, we measured the motor evoked potential (MEP). The more pulses of rTMS was applied, the smaller the amplitude of MEP became. From these results, it was found that the IRT of perceptual reversal and the amplitude of MEP primarily affected by the number of pulses of rTMS.
AB - The aim of this study is to investigate the stimulus parameter which affects the repetitive Transcranial Magnetic Stimulation (rTMS) effect. It is said that the condition under 1Hz rTMS induces the inhibition effect. On the other hand, the condition over 1Hz rTMS induces the facilitation effect. However the number of pulses of rTMS is also important factor. In this study, we focused on the number of pulses. We used the cognitive task of perceptual reversal and compared the rTMS effects of different condition under 1Hz which is the inhibition condition. It has been known that the right superior parietal lobule (SPL) has a role in perceptual reversal. We applied rTMS over the SPL and measured the inter-reversal time (IRT) of perceptual reversal. The results showed that when 0.25Hz 60pulses, 0.5Hz 60pulses and 1Hz 60pulses of rTMS was applied over the right SPL, the IRT was significantly smaller. On the other hand, when 1Hz 240pulses of rTMS was applied over the right SPL, the IRT was significantly longer. When 0.25Hz 120pulses, 0.5Hz 120pulses and 1Hz 120pulses of rTMS was applied over the right SPL, there were no significant differences. Furthermore, to investigate the rTMS effects, when rTMS are applied over the motor area, we measured the motor evoked potential (MEP). The more pulses of rTMS was applied, the smaller the amplitude of MEP became. From these results, it was found that the IRT of perceptual reversal and the amplitude of MEP primarily affected by the number of pulses of rTMS.
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U2 - 10.1109/IEMBS.2011.6091999
DO - 10.1109/IEMBS.2011.6091999
M3 - Conference contribution
C2 - 22256223
AN - SCOPUS:84861664252
SN - 9781424441211
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 8106
EP - 8109
BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
T2 - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Y2 - 30 August 2011 through 3 September 2011
ER -