Reversible electrical breakdown of bilayer lipid membranes with a ramped voltage and the quantitative analysis based on a transient aqueous pore model

J. Suehiro, H. Fujinobu, M. Hara

研究成果: Contribution to journalArticle査読

抄録

Reversible electrical breakdown of bilayer lipid membranes is observed by using the voltage-clamp method with ramped voltage waveforms. It is shown experimentally that the critical transmembrane voltage at which membrane conductance drastically increases depends on the ramp rate. The pore growing process is discussed quantitatively based on a transient pore model of the breakdown phenomena. The comparison between the experimental results and theoretical prediction shows that the model can describe the time course of the pore development and resultant increase in the membrane conductance. Effects of the voltage rising rate on the electroporation and the membrane conductance increase are discussed by using the transient pore model. (from Authors)

本文言語英語
ページ(範囲)263-277
ページ数15
ジャーナルMemoirs - Kyushu University, Faculty of Engineering
54
4
出版ステータス出版済み - 1994

All Science Journal Classification (ASJC) codes

  • Energy(all)
  • Atmospheric Science
  • Earth and Planetary Sciences(all)
  • Management of Technology and Innovation

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