Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides

Yuki Goto, Kazuhiro Iwasaki, Kohei Torikai, Hiroshi Murakami, Hiroaki Suga

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

抄録

We report here the ribosomal synthesis of methyllanthionine-containing cyclic peptides involving a site-specific incorporation of vinylglycine under the reprogrammed genetic code, followed by the isomerization of the vinylglycine to dehydrobutyrine, and the subsequent intramolecular Michael addition of a cysteine residue placed at a downstream position of the vinylglycine.

元の言語英語
ページ(範囲)3419-3421
ページ数3
ジャーナルChemical Communications
発行部数23
DOI
出版物ステータス出版済み - 8 7 2009
外部発表Yes

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Isomerization
Peptides
Cyclic Peptides
Cysteine
dehydrobutyrine
vinylglycine

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

これを引用

Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides. / Goto, Yuki; Iwasaki, Kazuhiro; Torikai, Kohei; Murakami, Hiroshi; Suga, Hiroaki.

:: Chemical Communications, 番号 23, 07.08.2009, p. 3419-3421.

研究成果: ジャーナルへの寄稿記事

Goto, Yuki ; Iwasaki, Kazuhiro ; Torikai, Kohei ; Murakami, Hiroshi ; Suga, Hiroaki. / Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides. :: Chemical Communications. 2009 ; 番号 23. pp. 3419-3421.
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