Risk Factors for and Outcomes of Intraoperative Blood Loss in Liver Resection for Hepatocellular Tumors

Daisuke Imai, Takashi Maeda, Huanlin Wang, Tomonari Shimagaki, Kensaku Sanefuji, Hiroto Kayashima, Shinichi Tsutsui, Hiroyuki Matsuda, Tomoharu Yoshizumi, Masaki Mori

研究成果: Contribution to journalArticle査読

抄録

Intraoperative blood loss (IBL) during liver resection is a predictor of morbidity, mortality, and tumor recurrence after hepatectomy; however, there have been few reports on patient factors associated with increased IBL. We enrolled consecutive patients who underwent liver resection for primary liver malignancies, and evaluated the predictors of IBL using a data set in which factors that might influence IBL, such as surgical devices, methods and anesthetic technique, were all standardized. We studied 244 patients. A multivariate analysis revealed that higher IBL was an independent risk factor for post-hepatectomy liver failure grade ≥B and overall survival. Multiple linear regression analyses showed serum creatinine, clinically significant portal hypertension (CSPH), tumor size, and major hepatectomy were all significant predictors of IBL. In conclusion, higher IBL was significantly associated with increased morbidity and mortality in patients with primary HCC who underwent liver resection. The risk of IBL was related to several factors including tumor size, serum creatinine, CSPH, and major hepatectomy.

本文言語英語
ページ(範囲)376-383
ページ数8
ジャーナルAmerican Surgeon
87
3
DOI
出版ステータス出版済み - 3 2021
外部発表はい

All Science Journal Classification (ASJC) codes

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