Risk factors for reduced salivary flow rate in a Japanese population

The Hisayama study

Kenji Takeuchi, Michiko Furuta, Toru Takeshita, Yukie Shibata, Yoshihiro Shimazaki, Sumio Akifusa, Toshiharu Ninomiya, Yutaka Kiyohara, Yoshihisa Yamashita

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

抄録

The purpose of this study was to determine distinct risk factors causing reduced salivary flow rate in a community-dwelling population using a prospective cohort study design. This was a 5-year follow-up survey of 1,377 community-dwelling Japanese individuals aged ≥40 years. The salivary flow rate was evaluated at baseline and follow-up by collecting stimulated saliva. Data on demographic characteristics, use of medication, and general and oral health status were obtained at baseline. The relationship between reduced salivary flow rate during the follow-up period and its predictors was evaluated after adjustment for confounding factors. In a multivariate logistic regression model, higher age and plaque score and lower serum albumin levels were significantly associated with greater odds of an obvious reduction in salivary flow rate (age per decade, odds ratio [OR] = 1.25, 95% confidence interval [CI] = 1.03-1.51; serum albumin levels <4 g/dL, OR = 1.60, 95% CI = 1.04-2.46; plaque score ≥1, OR = 1.53, 95% CI = 1.04-2.24). In a multivariate linear regression model, age and plaque score remained independently associated with the increased rate of reduced salivary flow. These results suggest that aging and plaque score are important predictors of reduced salivary flow rate in Japanese adults.

元の言語英語
記事番号381821
ジャーナルBioMed Research International
2015
DOI
出版物ステータス出版済み - 1 1 2015

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Independent Living
Odds Ratio
Flow rate
Confidence Intervals
Serum Albumin
Linear Models
Logistic Models
Population
Oral Health
Saliva
Health Status
Cohort Studies
Demography
Prospective Studies
Linear regression
Logistics
Aging of materials
Health
Surveys and Questionnaires

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

これを引用

Risk factors for reduced salivary flow rate in a Japanese population : The Hisayama study. / Takeuchi, Kenji; Furuta, Michiko; Takeshita, Toru; Shibata, Yukie; Shimazaki, Yoshihiro; Akifusa, Sumio; Ninomiya, Toshiharu; Kiyohara, Yutaka; Yamashita, Yoshihisa.

:: BioMed Research International, 巻 2015, 381821, 01.01.2015.

研究成果: ジャーナルへの寄稿記事

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