Risk stratification for congenital diaphragmatic hernia by factors within 24 h after birth

The Japanese Congenital Diaphragmatic Hernia Study Group

研究成果: ジャーナルへの寄稿学術誌査読

16 被引用数 (Scopus)

抄録

Objective: To establish a simple risk stratification system for patients with congenital diaphragmatic hernia (CDH) based on postnatal information within 24 h after birth. Study Design: A multi-institutional retrospective cohort study was conducted including 348 neonates who had isolated CDH born between 2006 and 2010. Based on the two most powerful variables for 90-day survival selected by multivariate analyses, a risk stratification system was established. Results: Multiple logistic regression analysis identified two adverse prognostic factors: an Apgar score at 1 min (Ap1) of 0-4 (odds ratio (OR) 3.3, P=0.004), and a best oxygenation index (OI) ≥ 3/48.0 (OR 11.4, P<0.001). Based on a combinations of these two factors, patients were classified into three risk categories. The 90-day survival rates in categories 1-3 were 100, 88 and 52%, respectively (P<0.001). Conclusion: Our simple risk stratification system based on Ap1 and best OI was capable of predicting mortality well.

本文言語英語
ページ(範囲)805-808
ページ数4
ジャーナルJournal of Perinatology
37
7
DOI
出版ステータス出版済み - 7月 1 2017

!!!All Science Journal Classification (ASJC) codes

  • 小児科学、周産期医学および子どもの健康
  • 産婦人科学

フィンガープリント

「Risk stratification for congenital diaphragmatic hernia by factors within 24 h after birth」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル