Role of 5-hydroxytryptamine 2C receptors in marble-burying behavior in mice

Nobuaki Egashira, Ryoko Okuno, Atsunori Shirakawa, Masaki Nagao, Kenichi Mishima, Katsunori Iwasaki, Ryozo Oishi, Michihiro Fujiwara

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

抜粋

We examined the role of 5-hydroxytryptamine 2C (5-HT 2C) receptors in marble-burying behavior in mice. When administered alone, the selective 5-HT 2C agonist WAY161503 (3 mg/kg) inhibited marble-burying behavior. Moreover, the selective 5-HT 2C antagonist SB242084 (3 mg/kg) reversed the inhibition of marble-burying behavior by 2,5-dimethoxy-4-iodoamphetamine (DOI) (1 mg/kg) or WAY161503 (3 mg/kg). Similarly, SB242084 (1 mg/kg) reversed the inhibition of marble-burying behavior by fluvoxamine (30 mg/kg) or paroxetine (3 mg/kg). These results suggest that 5-HT 2C receptors play a role in marble-burying behavior in mice.

元の言語英語
ページ(範囲)376-379
ページ数4
ジャーナルBiological and Pharmaceutical Bulletin
35
発行部数3
DOI
出版物ステータス出版済み - 3 1 2012

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science

これを引用

Egashira, N., Okuno, R., Shirakawa, A., Nagao, M., Mishima, K., Iwasaki, K., ... Fujiwara, M. (2012). Role of 5-hydroxytryptamine 2C receptors in marble-burying behavior in mice. Biological and Pharmaceutical Bulletin, 35(3), 376-379. https://doi.org/10.1248/bpb.35.376