TY - JOUR
T1 - Role of nitric oxide-detoxifying enzymes in the virulence of Pseudomonas aeruginosa against the silkworm, Bombyx mori
AU - Arai, Hiroyuki
AU - Iiyama, Kazuhiro
N1 - Funding Information:
This study was supported in part by a Grant-in-Aid from the Japan Society for the Promotion of Science (JSPS). We thank Takehiro Hirai for technical assistance.
PY - 2013
Y1 - 2013
N2 - Pseudomonas aeruginosa has two nitric oxide (NO)- detoxification enzymes, NO reductase and flavohemoglobin, which catalyze the reduction and oxygenation of NO respectively. In this study, the NO reductasedeficient mutant showed decreased virulence against the silkworm Bombyx mori, but the flavohemoglobindeficient mutant did not, indicating that NO-reduction is important to the full virulence of P. aeruginosa against B. mori.
AB - Pseudomonas aeruginosa has two nitric oxide (NO)- detoxification enzymes, NO reductase and flavohemoglobin, which catalyze the reduction and oxygenation of NO respectively. In this study, the NO reductasedeficient mutant showed decreased virulence against the silkworm Bombyx mori, but the flavohemoglobindeficient mutant did not, indicating that NO-reduction is important to the full virulence of P. aeruginosa against B. mori.
UR - http://www.scopus.com/inward/record.url?scp=84873528017&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84873528017&partnerID=8YFLogxK
U2 - 10.1271/bbb.120656
DO - 10.1271/bbb.120656
M3 - Article
C2 - 23291757
AN - SCOPUS:84873528017
VL - 77
SP - 198
EP - 200
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
SN - 0916-8451
IS - 1
ER -