Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients

Minako Inoue, Kiyoshi Matsumura, Yoshie Haga, Yasuo Kansui, Kenichi Goto, Toshio Ohtsubo, Takanari Kitazono

研究成果: Contribution to journalArticle

2 引用 (Scopus)

抜粋

The relationship between the renin–angiotensin aldosterone system and short-term blood pressure variability has not been well elucidated. Here, we investigated whether blood pressure variability determined by ambulatory blood pressure monitoring differed among patients with primary aldosteronism (PA), renovascular hypertension (RVHT), and essential hypertension (EHT). We examined 25 patients with PA, 28 patients with RVHT, and 18 patients with EHT. Ambulatory blood pressure monitoring was conducted in all patients. Short-term blood pressure variability was evaluated by calculating the standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) of 24-h, daytime, and nighttime blood pressure values. Day–night differences in blood pressure were also determined. The mean 24-h systolic blood pressure (SBP) and the mean diastolic blood pressure (DBP) in the PA and RVHT groups were found to be comparable to those in the EHT group. The SD, the CV, nor the ARV of the 24-h, daytime, and nighttime blood pressures showed any significant differences among the three groups. The day–night differences in blood pressure were comparable among the three groups. The short-term blood pressure variabilities evaluated by ambulatory blood pressure monitoring were comparable among the patients with EHT, RVHT, and PA. The results suggest that the renin–angiotensin aldosterone system may contribute little to short-term blood pressure variability in individuals with hypertension.

元の言語英語
ページ(範囲)624-630
ページ数7
ジャーナルClinical and Experimental Hypertension
40
発行部数7
DOI
出版物ステータス出版済み - 10 3 2018

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Physiology

フィンガープリント Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用