抄録
The relationship between the renin–angiotensin aldosterone system and short-term blood pressure variability has not been well elucidated. Here, we investigated whether blood pressure variability determined by ambulatory blood pressure monitoring differed among patients with primary aldosteronism (PA), renovascular hypertension (RVHT), and essential hypertension (EHT). We examined 25 patients with PA, 28 patients with RVHT, and 18 patients with EHT. Ambulatory blood pressure monitoring was conducted in all patients. Short-term blood pressure variability was evaluated by calculating the standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) of 24-h, daytime, and nighttime blood pressure values. Day–night differences in blood pressure were also determined. The mean 24-h systolic blood pressure (SBP) and the mean diastolic blood pressure (DBP) in the PA and RVHT groups were found to be comparable to those in the EHT group. The SD, the CV, nor the ARV of the 24-h, daytime, and nighttime blood pressures showed any significant differences among the three groups. The day–night differences in blood pressure were comparable among the three groups. The short-term blood pressure variabilities evaluated by ambulatory blood pressure monitoring were comparable among the patients with EHT, RVHT, and PA. The results suggest that the renin–angiotensin aldosterone system may contribute little to short-term blood pressure variability in individuals with hypertension.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 624-630 |
| ページ数 | 7 |
| ジャーナル | Clinical and Experimental Hypertension |
| 巻 | 40 |
| 発行部数 | 7 |
| DOI | |
| 出版物ステータス | 出版済み - 10 3 2018 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Internal Medicine
- Physiology
これを引用
Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients. / Inoue, Minako; Matsumura, Kiyoshi; Haga, Yoshie; Kansui, Yasuo; Goto, Kenichi; Ohtsubo, Toshio; Kitazono, Takanari.
：: Clinical and Experimental Hypertension, 巻 40, 番号 7, 03.10.2018, p. 624-630.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients
AU - Inoue, Minako
AU - Matsumura, Kiyoshi
AU - Haga, Yoshie
AU - Kansui, Yasuo
AU - Goto, Kenichi
AU - Ohtsubo, Toshio
AU - Kitazono, Takanari
PY - 2018/10/3
Y1 - 2018/10/3
N2 - The relationship between the renin–angiotensin aldosterone system and short-term blood pressure variability has not been well elucidated. Here, we investigated whether blood pressure variability determined by ambulatory blood pressure monitoring differed among patients with primary aldosteronism (PA), renovascular hypertension (RVHT), and essential hypertension (EHT). We examined 25 patients with PA, 28 patients with RVHT, and 18 patients with EHT. Ambulatory blood pressure monitoring was conducted in all patients. Short-term blood pressure variability was evaluated by calculating the standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) of 24-h, daytime, and nighttime blood pressure values. Day–night differences in blood pressure were also determined. The mean 24-h systolic blood pressure (SBP) and the mean diastolic blood pressure (DBP) in the PA and RVHT groups were found to be comparable to those in the EHT group. The SD, the CV, nor the ARV of the 24-h, daytime, and nighttime blood pressures showed any significant differences among the three groups. The day–night differences in blood pressure were comparable among the three groups. The short-term blood pressure variabilities evaluated by ambulatory blood pressure monitoring were comparable among the patients with EHT, RVHT, and PA. The results suggest that the renin–angiotensin aldosterone system may contribute little to short-term blood pressure variability in individuals with hypertension.
AB - The relationship between the renin–angiotensin aldosterone system and short-term blood pressure variability has not been well elucidated. Here, we investigated whether blood pressure variability determined by ambulatory blood pressure monitoring differed among patients with primary aldosteronism (PA), renovascular hypertension (RVHT), and essential hypertension (EHT). We examined 25 patients with PA, 28 patients with RVHT, and 18 patients with EHT. Ambulatory blood pressure monitoring was conducted in all patients. Short-term blood pressure variability was evaluated by calculating the standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) of 24-h, daytime, and nighttime blood pressure values. Day–night differences in blood pressure were also determined. The mean 24-h systolic blood pressure (SBP) and the mean diastolic blood pressure (DBP) in the PA and RVHT groups were found to be comparable to those in the EHT group. The SD, the CV, nor the ARV of the 24-h, daytime, and nighttime blood pressures showed any significant differences among the three groups. The day–night differences in blood pressure were comparable among the three groups. The short-term blood pressure variabilities evaluated by ambulatory blood pressure monitoring were comparable among the patients with EHT, RVHT, and PA. The results suggest that the renin–angiotensin aldosterone system may contribute little to short-term blood pressure variability in individuals with hypertension.
UR - http://www.scopus.com/inward/record.url?scp=85038089989&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85038089989&partnerID=8YFLogxK
U2 - 10.1080/10641963.2017.1416119
DO - 10.1080/10641963.2017.1416119
M3 - Article
C2 - 29244537
AN - SCOPUS:85038089989
VL - 40
SP - 624
EP - 630
JO - Clinical and Experimental Hypertension
JF - Clinical and Experimental Hypertension
SN - 1064-1963
IS - 7
ER -