Role of the P2X4 receptor in neuropathic pain

Kazuhide Inoue

研究成果: Contribution to journalReview article査読

18 被引用数 (Scopus)

抄録

Neuropathic pain is the most important type of chronic pain because it is refractory to available medications. Neuropathic pain occurs after peripheral nerve injury (PNI) or nerve damage by various reasons. In recent decades, a growing body of evidence shows that spinal microglia and P2X4 receptor (P2X4R), a subtype of ionotropic ATP receptors, play a principal role in evoking this pain. Understanding the functions of microglial P2X4R in evoking this pain provides potential strategies for developing new treatments for neuropathic pain.

本文言語英語
ページ(範囲)33-39
ページ数7
ジャーナルCurrent Opinion in Pharmacology
47
DOI
出版ステータス出版済み - 8 2019

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

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