ROS-mediated synthetic growth defect caused by impaired metabolism of sphingolipids and phosphatidylserine in budding yeast

Takumi Toda, Atsuya Urita, Ayano Koga, Chihiro Takayama, Motohiro Tani

研究成果: Contribution to journalArticle査読

抄録

Previously, we found that yeast exhibits a strong growth defect with the combination of a lack of gene involved in structural modification of sphingolipids and repression of the phosphatidylserine synthase gene. Here we found that the double gene mutation causes reactive oxygen species-mediated cell growth defect, which is suppressed by deletion of LEM3 encoding the subunit of phospholipid flippase.

本文言語英語
ページ(範囲)2529-2532
ページ数4
ジャーナルBioscience, Biotechnology and Biochemistry
84
12
DOI
出版ステータス出版済み - 12 1 2020

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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