Rote of Ca2+ in the formation of an excitable membrane on the surface of a protoplasmic droplet of nitella

Kiyoshi Toko, Kaoru Yamafuji

研究成果: Contribution to journalArticle査読

6 被引用数 (Scopus)

抄録

A theory is presented for a phase transition between resting and depolarized states of a protoplasmic droplet of Nitella induced by variation of Ca2+ and Na+ concentrations. In the theory, a membrane formed on a surface of the droplet by lipids and proteins is regarded as a kind of adsorbed bilayer. Effects of bridging among adsorbed molecules through Ca2+ are taken into account, besides an electrostatic interaction between polar groups of adsorbed molecules and monovalent and divalent cations. It is shown that an excitable membrane is stabilized only in a certain range of Ca2+ and Na+ concentrations, where a phase separation through the Ca2+-bridging occurs between Ca2+-rich membranous and Ca2+-depleted domains. This kind of phase separation is mainly subject to a competitive effect between monovalent cations and Ca2+ at lower Ca2+ concentrations but an ionic strength at higher Ca2+ concentrations. The present results can explain fairly well quantitative features of existing observed data.

本文言語英語
ページ(範囲)461-478
ページ数18
ジャーナルJournal of Theoretical Biology
99
3
DOI
出版ステータス出版済み - 12 7 1982

All Science Journal Classification (ASJC) codes

  • 統計学および確率
  • モデリングとシミュレーション
  • 生化学、遺伝学、分子生物学(全般)
  • 免疫学および微生物学(全般)
  • 農業および生物科学(全般)
  • 応用数学

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