rRNA degradation in Bombyx mori and Bombyx mandarina cells infected witv veterologous nucleopolyvedroviruses

Rina Hamajima, Chisa Yasunaga-Aoki, Masashi Iwanaga, Shigeo Imanishi, Jun Kobayashi, Kuni Sasaki, Takahiro Kusakabe, Man Lee, Hiroaki Mon, Michihiro Kobayashi, Motoko Ikeda

研究成果: ジャーナルへの寄稿記事

抄録

We previously found that rRNA of BM-N cells derived from the silkworm Bombyx mori undergoes rapid and extensive degradation through site-specific cleavage during abortive infection with nucleopolyhedroviruses (NPVs) of Autographa californica (AcMNPV), Hyphantria cunea (HycuMNPV), Spodoptera exigua and S. litura. Here, we demonstrated that rRNA degradation also occurs in Bme21 and Bm-aff3 cells, which are derived from B. mori embryo and fat body, respectively, during infection with AcMNPV. rRNA degradation in Bme21 cells was also observed following HycuMNPV infection, but was not detected in Bm-aff3 cells. We further showed that rRNA in a cell line derived from B. mandarina, an ancestor of B. mori, underwent degradation in response to cellular infection with AcMNPV and HycuMNPV. In contrast, no rRNA degradation was observed in a cell line derived from Antheraea pernyi. Taken together, these results indicate that NPV-triggered rRNA degradation represents a mechanism of innate antiviral immunity that is unique to B. mori and B. mandarina cells.

元の言語英語
ページ(範囲)73-77
ページ数5
ジャーナルJournal of Insect Biotechnology and Sericology
85
発行部数3
出版物ステータス出版済み - 1 1 2016

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Bombyx
Bombyx mori
ribosomal RNA
Autographa californica multiple nucleopolyhedrovirus
Degradation
degradation
Nucleopolyhedrovirus
Infection
Baculoviridae
cells
infection
Cell Line
Spodoptera
Antheraea pernyi
Cells
cell lines
Hyphantria cunea
Autographa californica
Fat Body
Moths

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Business, Management and Accounting(all)
  • Agricultural and Biological Sciences(all)
  • Insect Science
  • Industrial and Manufacturing Engineering

これを引用

rRNA degradation in Bombyx mori and Bombyx mandarina cells infected witv veterologous nucleopolyvedroviruses. / Hamajima, Rina; Yasunaga-Aoki, Chisa; Iwanaga, Masashi; Imanishi, Shigeo; Kobayashi, Jun; Sasaki, Kuni; Kusakabe, Takahiro; Lee, Man; Mon, Hiroaki; Kobayashi, Michihiro; Ikeda, Motoko.

:: Journal of Insect Biotechnology and Sericology, 巻 85, 番号 3, 01.01.2016, p. 73-77.

研究成果: ジャーナルへの寄稿記事

Hamajima, R, Yasunaga-Aoki, C, Iwanaga, M, Imanishi, S, Kobayashi, J, Sasaki, K, Kusakabe, T, Lee, M, Mon, H, Kobayashi, M & Ikeda, M 2016, 'rRNA degradation in Bombyx mori and Bombyx mandarina cells infected witv veterologous nucleopolyvedroviruses', Journal of Insect Biotechnology and Sericology, 巻. 85, 番号 3, pp. 73-77.
Hamajima, Rina ; Yasunaga-Aoki, Chisa ; Iwanaga, Masashi ; Imanishi, Shigeo ; Kobayashi, Jun ; Sasaki, Kuni ; Kusakabe, Takahiro ; Lee, Man ; Mon, Hiroaki ; Kobayashi, Michihiro ; Ikeda, Motoko. / rRNA degradation in Bombyx mori and Bombyx mandarina cells infected witv veterologous nucleopolyvedroviruses. :: Journal of Insect Biotechnology and Sericology. 2016 ; 巻 85, 番号 3. pp. 73-77.
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abstract = "We previously found that rRNA of BM-N cells derived from the silkworm Bombyx mori undergoes rapid and extensive degradation through site-specific cleavage during abortive infection with nucleopolyhedroviruses (NPVs) of Autographa californica (AcMNPV), Hyphantria cunea (HycuMNPV), Spodoptera exigua and S. litura. Here, we demonstrated that rRNA degradation also occurs in Bme21 and Bm-aff3 cells, which are derived from B. mori embryo and fat body, respectively, during infection with AcMNPV. rRNA degradation in Bme21 cells was also observed following HycuMNPV infection, but was not detected in Bm-aff3 cells. We further showed that rRNA in a cell line derived from B. mandarina, an ancestor of B. mori, underwent degradation in response to cellular infection with AcMNPV and HycuMNPV. In contrast, no rRNA degradation was observed in a cell line derived from Antheraea pernyi. Taken together, these results indicate that NPV-triggered rRNA degradation represents a mechanism of innate antiviral immunity that is unique to B. mori and B. mandarina cells.",
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T1 - rRNA degradation in Bombyx mori and Bombyx mandarina cells infected witv veterologous nucleopolyvedroviruses

AU - Hamajima, Rina

AU - Yasunaga-Aoki, Chisa

AU - Iwanaga, Masashi

AU - Imanishi, Shigeo

AU - Kobayashi, Jun

AU - Sasaki, Kuni

AU - Kusakabe, Takahiro

AU - Lee, Man

AU - Mon, Hiroaki

AU - Kobayashi, Michihiro

AU - Ikeda, Motoko

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