rRNA degradation in Bombyx mori and Bombyx mandarina cells infected witv veterologous nucleopolyvedroviruses

Rina Hamajima, Chisa Yasunaga-Aoki, Masashi Iwanaga, Shigeo Imanishi, Jun Kobayashi, Kuni Sasaki, Takahiro Kusakabe, Jae Man Lee, Hiroaki Mon, Michihiro Kobayashi, Motoko Ikeda

研究成果: Contribution to journalArticle査読

抄録

We previously found that rRNA of BM-N cells derived from the silkworm Bombyx mori undergoes rapid and extensive degradation through site-specific cleavage during abortive infection with nucleopolyhedroviruses (NPVs) of Autographa californica (AcMNPV), Hyphantria cunea (HycuMNPV), Spodoptera exigua and S. litura. Here, we demonstrated that rRNA degradation also occurs in Bme21 and Bm-aff3 cells, which are derived from B. mori embryo and fat body, respectively, during infection with AcMNPV. rRNA degradation in Bme21 cells was also observed following HycuMNPV infection, but was not detected in Bm-aff3 cells. We further showed that rRNA in a cell line derived from B. mandarina, an ancestor of B. mori, underwent degradation in response to cellular infection with AcMNPV and HycuMNPV. In contrast, no rRNA degradation was observed in a cell line derived from Antheraea pernyi. Taken together, these results indicate that NPV-triggered rRNA degradation represents a mechanism of innate antiviral immunity that is unique to B. mori and B. mandarina cells.

本文言語英語
ページ(範囲)73-77
ページ数5
ジャーナルJournal of Insect Biotechnology and Sericology
85
3
出版ステータス出版済み - 2016

All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • 応用微生物学とバイオテクノロジー
  • ビジネス、管理および会計(全般)
  • 農業および生物科学(全般)
  • 昆虫科学
  • 産業および生産工学

フィンガープリント

「rRNA degradation in Bombyx mori and Bombyx mandarina cells infected witv veterologous nucleopolyvedroviruses」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル