Saposin D: a sphingomyelinase activator

S Morimoto, B M Martin, Y Kishimoto, J S O'Brien

研究成果: Contribution to journalArticle査読

95 被引用数 (Scopus)

抄録

Saposin D, a newly discovered heat-stable, 10 kDa glycoprotein, was isolated from Gaucher spleen and purified to homogeneity. Chemical sequencing from its amino terminus demonstrated colinearity between its amino acid sequence and the deduced amino acid sequence of the fourth domain of prosaposin, the precursor of saposin proteins. Saposin D specifically stimulates acid sphingomyelinase but has no significant effect on the other hydrolases tested.

本文言語英語
ページ(範囲)403-10
ページ数8
ジャーナルBiochemical and Biophysical Research Communications
156
1
出版ステータス出版済み - 10 14 1988

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