Scattered and rapid intrahepatic recurrences after radio frequency ablation for hepatocellular carcinoma

Kazuhiro Kotoh, Munechika Enjoji, Eiichirou Arimura, Shusuke Morizono, Motoyuki Kohjima, Hironori Sakai, Makoto Nakamuta

研究成果: ジャーナルへの寄稿記事

36 引用 (Scopus)

抄録

Aim: To evaluate a series of patients with hepatocellular carcinoma (HCC) treated with several different protocols and devices. Methods: We treated 138 patients [chronic hepatitis/liver cirrhosis (Child-Pugh A/B/C), 3/135 (107/25/3)] with two different devices and protocols: cool-tip needle [initial ablation at 60 W (standard method) (n = 37) or at 40 W (modified method) (n = 28)] or; ablation with a LeVeen needle using a standard single-step, full expansion (single-step) method (n = 39) or a multi-step, incremental expansion (multi-step) method. Results: Eleven patients experienced rapid and scattered recurrences 1 to 7 mo after the ablation. Nine patients were treated by the cool-tip original protocol (60 W) (9/37 = 24%) and the other two by the LeVeen single-step method (2/39 = 5%). The location of the recurrence was surrounding and limited to the site of ablation segment in three cases, and spread over one lobule or both lobules in the other eight cases. There was no recurrence in the patients treated with the modified cool-tip modified method (40 W) or the LeVeen multi-step method. Conclusion: There is a risk of rapid and scattered recurrence after RFA, especially when the standard cool-tip procedure is used. Because such recurrence would worsen the prognosis, we recommend that modified protocols for the cool-tip and LeVeen needle methods should be used in clinical practice.

元の言語英語
ページ(範囲)6828-6832
ページ数5
ジャーナルWorld Journal of Gastroenterology
11
発行部数43
DOI
出版物ステータス出版済み - 11 21 2005

Fingerprint

Radio
Hepatocellular Carcinoma
Recurrence
Needles
Equipment and Supplies
Chronic Hepatitis
Liver Cirrhosis

All Science Journal Classification (ASJC) codes

  • Gastroenterology

これを引用

Scattered and rapid intrahepatic recurrences after radio frequency ablation for hepatocellular carcinoma. / Kotoh, Kazuhiro; Enjoji, Munechika; Arimura, Eiichirou; Morizono, Shusuke; Kohjima, Motoyuki; Sakai, Hironori; Nakamuta, Makoto.

:: World Journal of Gastroenterology, 巻 11, 番号 43, 21.11.2005, p. 6828-6832.

研究成果: ジャーナルへの寄稿記事

Kotoh, Kazuhiro ; Enjoji, Munechika ; Arimura, Eiichirou ; Morizono, Shusuke ; Kohjima, Motoyuki ; Sakai, Hironori ; Nakamuta, Makoto. / Scattered and rapid intrahepatic recurrences after radio frequency ablation for hepatocellular carcinoma. :: World Journal of Gastroenterology. 2005 ; 巻 11, 番号 43. pp. 6828-6832.
@article{b11ef009d90a4de2adc257cc1c260a5c,
title = "Scattered and rapid intrahepatic recurrences after radio frequency ablation for hepatocellular carcinoma",
abstract = "Aim: To evaluate a series of patients with hepatocellular carcinoma (HCC) treated with several different protocols and devices. Methods: We treated 138 patients [chronic hepatitis/liver cirrhosis (Child-Pugh A/B/C), 3/135 (107/25/3)] with two different devices and protocols: cool-tip needle [initial ablation at 60 W (standard method) (n = 37) or at 40 W (modified method) (n = 28)] or; ablation with a LeVeen needle using a standard single-step, full expansion (single-step) method (n = 39) or a multi-step, incremental expansion (multi-step) method. Results: Eleven patients experienced rapid and scattered recurrences 1 to 7 mo after the ablation. Nine patients were treated by the cool-tip original protocol (60 W) (9/37 = 24{\%}) and the other two by the LeVeen single-step method (2/39 = 5{\%}). The location of the recurrence was surrounding and limited to the site of ablation segment in three cases, and spread over one lobule or both lobules in the other eight cases. There was no recurrence in the patients treated with the modified cool-tip modified method (40 W) or the LeVeen multi-step method. Conclusion: There is a risk of rapid and scattered recurrence after RFA, especially when the standard cool-tip procedure is used. Because such recurrence would worsen the prognosis, we recommend that modified protocols for the cool-tip and LeVeen needle methods should be used in clinical practice.",
author = "Kazuhiro Kotoh and Munechika Enjoji and Eiichirou Arimura and Shusuke Morizono and Motoyuki Kohjima and Hironori Sakai and Makoto Nakamuta",
year = "2005",
month = "11",
day = "21",
doi = "10.3748/wjg.v11.i43.6828",
language = "English",
volume = "11",
pages = "6828--6832",
journal = "World Journal of Gastroenterology",
issn = "1007-9327",
publisher = "WJG Press",
number = "43",

}

TY - JOUR

T1 - Scattered and rapid intrahepatic recurrences after radio frequency ablation for hepatocellular carcinoma

AU - Kotoh, Kazuhiro

AU - Enjoji, Munechika

AU - Arimura, Eiichirou

AU - Morizono, Shusuke

AU - Kohjima, Motoyuki

AU - Sakai, Hironori

AU - Nakamuta, Makoto

PY - 2005/11/21

Y1 - 2005/11/21

N2 - Aim: To evaluate a series of patients with hepatocellular carcinoma (HCC) treated with several different protocols and devices. Methods: We treated 138 patients [chronic hepatitis/liver cirrhosis (Child-Pugh A/B/C), 3/135 (107/25/3)] with two different devices and protocols: cool-tip needle [initial ablation at 60 W (standard method) (n = 37) or at 40 W (modified method) (n = 28)] or; ablation with a LeVeen needle using a standard single-step, full expansion (single-step) method (n = 39) or a multi-step, incremental expansion (multi-step) method. Results: Eleven patients experienced rapid and scattered recurrences 1 to 7 mo after the ablation. Nine patients were treated by the cool-tip original protocol (60 W) (9/37 = 24%) and the other two by the LeVeen single-step method (2/39 = 5%). The location of the recurrence was surrounding and limited to the site of ablation segment in three cases, and spread over one lobule or both lobules in the other eight cases. There was no recurrence in the patients treated with the modified cool-tip modified method (40 W) or the LeVeen multi-step method. Conclusion: There is a risk of rapid and scattered recurrence after RFA, especially when the standard cool-tip procedure is used. Because such recurrence would worsen the prognosis, we recommend that modified protocols for the cool-tip and LeVeen needle methods should be used in clinical practice.

AB - Aim: To evaluate a series of patients with hepatocellular carcinoma (HCC) treated with several different protocols and devices. Methods: We treated 138 patients [chronic hepatitis/liver cirrhosis (Child-Pugh A/B/C), 3/135 (107/25/3)] with two different devices and protocols: cool-tip needle [initial ablation at 60 W (standard method) (n = 37) or at 40 W (modified method) (n = 28)] or; ablation with a LeVeen needle using a standard single-step, full expansion (single-step) method (n = 39) or a multi-step, incremental expansion (multi-step) method. Results: Eleven patients experienced rapid and scattered recurrences 1 to 7 mo after the ablation. Nine patients were treated by the cool-tip original protocol (60 W) (9/37 = 24%) and the other two by the LeVeen single-step method (2/39 = 5%). The location of the recurrence was surrounding and limited to the site of ablation segment in three cases, and spread over one lobule or both lobules in the other eight cases. There was no recurrence in the patients treated with the modified cool-tip modified method (40 W) or the LeVeen multi-step method. Conclusion: There is a risk of rapid and scattered recurrence after RFA, especially when the standard cool-tip procedure is used. Because such recurrence would worsen the prognosis, we recommend that modified protocols for the cool-tip and LeVeen needle methods should be used in clinical practice.

UR - http://www.scopus.com/inward/record.url?scp=30744453991&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=30744453991&partnerID=8YFLogxK

U2 - 10.3748/wjg.v11.i43.6828

DO - 10.3748/wjg.v11.i43.6828

M3 - Article

C2 - 16425391

AN - SCOPUS:30744453991

VL - 11

SP - 6828

EP - 6832

JO - World Journal of Gastroenterology

JF - World Journal of Gastroenterology

SN - 1007-9327

IS - 43

ER -