Second-generation synthesis of endogenous sperm-activating and attracting factor (SAAF) isolated from the ascidian Ciona intestinalis

Tohru Oishi, Kouichiro Ootou, Hajime Shibata, Michio Murata

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

抄録

Stereoselective synthesis of the chemoattractant sperm-activating and attracting factor (SAAF), isolated from the eggs of the ascidian Ciona intestinalis, was achieved via reductive 1,3-transposition of an allylic alcohol and the axial opening of an epoxide as key steps. This second-generation synthesis improved the total yield of SAAF over that of the first-generation synthesis and provided a key intermediate for synthesizing molecular probes of SAAF.

元の言語英語
ページ(範囲)2600-2602
ページ数3
ジャーナルTetrahedron Letters
51
発行部数19
DOI
出版物ステータス出版済み - 5 12 2010
外部発表Yes

Fingerprint

Ciona intestinalis
Urochordata
Spermatozoa
Molecular Probes
Epoxy Compounds
Chemotactic Factors
Eggs

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

これを引用

Second-generation synthesis of endogenous sperm-activating and attracting factor (SAAF) isolated from the ascidian Ciona intestinalis. / Oishi, Tohru; Ootou, Kouichiro; Shibata, Hajime; Murata, Michio.

:: Tetrahedron Letters, 巻 51, 番号 19, 12.05.2010, p. 2600-2602.

研究成果: ジャーナルへの寄稿記事

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