Selection of poly(lactide)s binding peptides from phage displayed peptide library

Hisao Matsuno, Jun Sekine, Hirohumi Yajima, Takeshi Seizawa

研究成果: Contribution to conferencePaper査読

抄録

Structurally well-defined synthetic polymers with stereoregularity, chirality, helicity, and assembly are versatile materials for conjugation with biomolecules, and hybridization of these polymers with various biomolecules such as polypeptide and protein will expand its potentialities for biomedical applications. In this paper, peptides that bind to poly(L-lactide) (PLLA) were selected from the 7-mer peptide library. The spin coated film of PLLA was formed on a glass plate, and the biopanning was carried out on the film with the phage display peptide library. After four rounds of biopanning, sixteen individual sequences were obtained from the 30 phage clones. We quantified the binding property between the selected peptides and PLLA by the enzyme linked immunosorbent assay (ELISA).

本文言語英語
ページ数1
出版ステータス出版済み - 10 19 2006
外部発表はい
イベント55th SPSJ Annual Meeting - Nagoya, 日本
継続期間: 5 24 20065 26 2006

その他

その他55th SPSJ Annual Meeting
Country日本
CityNagoya
Period5/24/065/26/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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